Immunopathogenesis of dilated cardiomyopathies
Idiopathic dilated cardiomyopathy is a chronic heart muscle disorder of unknown etiology, but experimental and clinical evidence is accumulating that points to an immune pathogenesis in a subset of patients, and to the potential importance of myosin as an antigen. Most recent developments include ev...
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| Veröffentlicht in: | Current opinion in cardiology 1995-05, Vol.10 (3), p.306-311 |
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| container_title | Current opinion in cardiology |
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| creator | Goldman, Jonathan H McKenna, William J |
| description | Idiopathic dilated cardiomyopathy is a chronic heart muscle disorder of unknown etiology, but experimental and clinical evidence is accumulating that points to an immune pathogenesis in a subset of patients, and to the potential importance of myosin as an antigen. Most recent developments include evidence of cardiac- and disease-specific autoantibodies in a proportion of patients with dilated cardiomyopathy and their relatives, and the identification of immunogenic epitopes. |
| doi_str_mv | 10.1097/00001573-199505000-00012 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0268-4705 |
| ispartof | Current opinion in cardiology, 1995-05, Vol.10 (3), p.306-311 |
| issn | 0268-4705 1531-7080 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77390149 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | AIDS/HIV Animals Autoantibodies - analysis Cardiomyopathy, Dilated - etiology Cardiomyopathy, Dilated - immunology HIV Infections - complications Humans Mice Myosins - immunology |
| title | Immunopathogenesis of dilated cardiomyopathies |
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