Usefulness of Q-wave response to exercise as a predictor of coronary artery disease
In lead CM 5, the Q-wave response to exercise has been reported as an effective index in predicting coronary artery disease (CAD) and CAD with left anterior descending (LAD) disease. The purpose of this study was to verify these findings when the Q wave was analyzed in lead CC 5 in 135 patients. The...
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| Veröffentlicht in: | The American journal of cardiology 1987, Vol.59 (1), p.57-60 |
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| creator | Furuse, Tomoyuki Mashiba, Hiroto Jordan, John W. O'Donnell, Jacqueline Morris, Stephen N. McHenry, Paul L. |
| description | In lead CM
5, the Q-wave response to exercise has been reported as an effective index in predicting coronary artery disease (CAD) and CAD with left anterior descending (LAD) disease. The purpose of this study was to verify these findings when the Q wave was analyzed in lead CC
5 in 135 patients. The sensitivity for abnormal ST depression was 77%, specificity 83% and predictive value 78%. The corresponding values for the abnormal Q-wave response (reduction or no change in Q-wave amplitude) were 70%, 61% and 59%. These differences (except sensitivity) were significant. When either a positive ST or Q-wave response was used, sensitivity, specificity and predictive value did not significantly increase compared with the ST segment alone. In addition, only 45% of normal subjects with false-positive ST depression had a normal Q-wave response (increase) and 57% of patients with false-negative ST responses had an abnormal Q-wave response. When a positive response for CAD with an LAD lesion and for multivessel CAD with LAD narrowing was defined as having a Q-wave reduction, the sensitivities were extremely low (15% and 17%), but both the specificities and the predictive values were 100%. Therefore, the Q-wave analysis in lead CC
5 is no more sensitive for detecting CAD than the ST-segment response. However, when a decreased Q-wave amplitude is observed, multivessel CAD with LAD narrowing can be predicted. |
| doi_str_mv | 10.1016/S0002-9149(87)80069-3 |
| format | Article |
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5 in 135 patients. The sensitivity for abnormal ST depression was 77%, specificity 83% and predictive value 78%. The corresponding values for the abnormal Q-wave response (reduction or no change in Q-wave amplitude) were 70%, 61% and 59%. These differences (except sensitivity) were significant. When either a positive ST or Q-wave response was used, sensitivity, specificity and predictive value did not significantly increase compared with the ST segment alone. In addition, only 45% of normal subjects with false-positive ST depression had a normal Q-wave response (increase) and 57% of patients with false-negative ST responses had an abnormal Q-wave response. When a positive response for CAD with an LAD lesion and for multivessel CAD with LAD narrowing was defined as having a Q-wave reduction, the sensitivities were extremely low (15% and 17%), but both the specificities and the predictive values were 100%. Therefore, the Q-wave analysis in lead CC
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5, the Q-wave response to exercise has been reported as an effective index in predicting coronary artery disease (CAD) and CAD with left anterior descending (LAD) disease. The purpose of this study was to verify these findings when the Q wave was analyzed in lead CC
5 in 135 patients. The sensitivity for abnormal ST depression was 77%, specificity 83% and predictive value 78%. The corresponding values for the abnormal Q-wave response (reduction or no change in Q-wave amplitude) were 70%, 61% and 59%. These differences (except sensitivity) were significant. When either a positive ST or Q-wave response was used, sensitivity, specificity and predictive value did not significantly increase compared with the ST segment alone. In addition, only 45% of normal subjects with false-positive ST depression had a normal Q-wave response (increase) and 57% of patients with false-negative ST responses had an abnormal Q-wave response. When a positive response for CAD with an LAD lesion and for multivessel CAD with LAD narrowing was defined as having a Q-wave reduction, the sensitivities were extremely low (15% and 17%), but both the specificities and the predictive values were 100%. Therefore, the Q-wave analysis in lead CC
5 is no more sensitive for detecting CAD than the ST-segment response. However, when a decreased Q-wave amplitude is observed, multivessel CAD with LAD narrowing can be predicted.</description><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Coronary Disease - diagnosis</subject><subject>Coronary Disease - pathology</subject><subject>Coronary heart disease</subject><subject>Electrocardiography - standards</subject><subject>Forecasting</subject><subject>Heart</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Physical Exertion</subject><subject>Retrospective Studies</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoMotVZ_QmEPInpYTZrdTXISKX5BQaT2HNJkAivbTc1sq_570w969TQT5pm8w0PIkNFbRll1N6WUjnLFCnUtxY2ktFI5PyJ9JoXKmWL8mPQPyCk5Q_xMT8bKqkd6XLLRqOR9Mp0h-FXTAmIWfPaef5s1ZBFwGVqErAsZ_EC0deoNZiZbRnC17ULc0DbE0Jr4m5nYQSouYQbhnJx40yBc7OuAzJ4eP8Yv-eTt-XX8MMktl6rLjRRzD67y3HmvXGUFMKuElNRSUVRC-EIU3vm5LUpXUmnmRhWOi1GlTKEY5QNytft3GcPXCrDTixotNI1pIaxQC5FyJBMJLHegjQExgtfLWC_S4ZpRvZGptzL1xpSWQm9lap72hvuA1XwB7rC1t5fml_u5QWsaH02bTB0wSRkt1Sb-fodBkrGuIWq0NbQ2mYxgO-1C_c8hf3_2kTw</recordid><startdate>1987</startdate><enddate>1987</enddate><creator>Furuse, Tomoyuki</creator><creator>Mashiba, Hiroto</creator><creator>Jordan, John W.</creator><creator>O'Donnell, Jacqueline</creator><creator>Morris, Stephen N.</creator><creator>McHenry, Paul L.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1987</creationdate><title>Usefulness of Q-wave response to exercise as a predictor of coronary artery disease</title><author>Furuse, Tomoyuki ; Mashiba, Hiroto ; Jordan, John W. ; O'Donnell, Jacqueline ; Morris, Stephen N. ; McHenry, Paul L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-a87bfed6f3dff9d6c7e1c97880c074677f474fdfbc45d508aba94d37269a49103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Coronary Disease - diagnosis</topic><topic>Coronary Disease - pathology</topic><topic>Coronary heart disease</topic><topic>Electrocardiography - standards</topic><topic>Forecasting</topic><topic>Heart</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Physical Exertion</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Furuse, Tomoyuki</creatorcontrib><creatorcontrib>Mashiba, Hiroto</creatorcontrib><creatorcontrib>Jordan, John W.</creatorcontrib><creatorcontrib>O'Donnell, Jacqueline</creatorcontrib><creatorcontrib>Morris, Stephen N.</creatorcontrib><creatorcontrib>McHenry, Paul L.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Furuse, Tomoyuki</au><au>Mashiba, Hiroto</au><au>Jordan, John W.</au><au>O'Donnell, Jacqueline</au><au>Morris, Stephen N.</au><au>McHenry, Paul L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Usefulness of Q-wave response to exercise as a predictor of coronary artery disease</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>1987</date><risdate>1987</risdate><volume>59</volume><issue>1</issue><spage>57</spage><epage>60</epage><pages>57-60</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>In lead CM
5, the Q-wave response to exercise has been reported as an effective index in predicting coronary artery disease (CAD) and CAD with left anterior descending (LAD) disease. The purpose of this study was to verify these findings when the Q wave was analyzed in lead CC
5 in 135 patients. The sensitivity for abnormal ST depression was 77%, specificity 83% and predictive value 78%. The corresponding values for the abnormal Q-wave response (reduction or no change in Q-wave amplitude) were 70%, 61% and 59%. These differences (except sensitivity) were significant. When either a positive ST or Q-wave response was used, sensitivity, specificity and predictive value did not significantly increase compared with the ST segment alone. In addition, only 45% of normal subjects with false-positive ST depression had a normal Q-wave response (increase) and 57% of patients with false-negative ST responses had an abnormal Q-wave response. When a positive response for CAD with an LAD lesion and for multivessel CAD with LAD narrowing was defined as having a Q-wave reduction, the sensitivities were extremely low (15% and 17%), but both the specificities and the predictive values were 100%. Therefore, the Q-wave analysis in lead CC
5 is no more sensitive for detecting CAD than the ST-segment response. However, when a decreased Q-wave amplitude is observed, multivessel CAD with LAD narrowing can be predicted.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3812253</pmid><doi>10.1016/S0002-9149(87)80069-3</doi><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Biological and medical sciences Cardiology. Vascular system Coronary Disease - diagnosis Coronary Disease - pathology Coronary heart disease Electrocardiography - standards Forecasting Heart Humans Medical sciences Physical Exertion Retrospective Studies |
| title | Usefulness of Q-wave response to exercise as a predictor of coronary artery disease |
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