Tectal transplants into the occipital cortex of the newborn rat
Embryonic day 15 rostral tectum (presumptive superior colliculus) was transplanted into the occipital cortex of newborn rats. One to two months later, the transplants were visualized and injected with either horseradish peroxidase (HRP) or wheat germ agglutinin conjugated with HRP (WGA/HRP). After t...
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| Veröffentlicht in: | Brain research 1987, Vol.31 (1), p.119-123 |
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| container_title | Brain research |
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| creator | Sharkey, Mary Ann Steedman, John G. Lund, Raymond D. Dom, Richard M. |
| description | Embryonic day 15 rostral tectum (presumptive superior colliculus) was transplanted into the occipital cortex of newborn rats. One to two months later, the transplants were visualized and injected with either horseradish peroxidase (HRP) or wheat germ agglutinin conjugated with HRP (WGA/HRP). After the appropriate survival time and processing with either diaminobenzidine (DAB) or tetramethylbenzidine tetrahydrochloride (TMB), HRP-labelled pyramidal cells were found in layer V of the host ipsilateral occipital cortex. Thus, the occipitotectal connections are formed between host and graft despite the fact that the fibers must grow in a direction opposite to their normal course to reach the aberrantly positioned tectal graft. |
| doi_str_mv | 10.1016/0165-3806(87)90088-5 |
| format | Article |
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One to two months later, the transplants were visualized and injected with either horseradish peroxidase (HRP) or wheat germ agglutinin conjugated with HRP (WGA/HRP). After the appropriate survival time and processing with either diaminobenzidine (DAB) or tetramethylbenzidine tetrahydrochloride (TMB), HRP-labelled pyramidal cells were found in layer V of the host ipsilateral occipital cortex. Thus, the occipitotectal connections are formed between host and graft despite the fact that the fibers must grow in a direction opposite to their normal course to reach the aberrantly positioned tectal graft.</description><identifier>ISSN: 0165-3806</identifier><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/0165-3806(87)90088-5</identifier><identifier>PMID: 3028580</identifier><identifier>CODEN: BRREAP</identifier><language>eng</language><publisher>London: Elsevier B.V</publisher><subject>Animals ; Animals, Newborn - physiology ; Biological and medical sciences ; Connectional selectivity ; Eye and associated structures. Visual pathways and centers. Vision ; Fundamental and applied biological sciences. Psychology ; Horseradish Peroxidase ; Layer V ; Nerve Fibers - physiology ; Neural Pathways - physiology ; Occipital cortex ; Occipital Lobe - physiology ; Occipital Lobe - surgery ; Pyramidal cell ; Rats ; Rats, Inbred Strains ; Synaptic Transmission ; Tectum ; Tectum Mesencephali - physiology ; Tectum Mesencephali - transplantation ; Transplantation ; Vertebrates: nervous system and sense organs</subject><ispartof>Brain research, 1987, Vol.31 (1), p.119-123</ispartof><rights>1987</rights><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c454t-5169d1b3cf18001ebcaa383aed773fa553d52a793dc4e826cf10ddb4fe32e9913</citedby><cites>FETCH-LOGICAL-c454t-5169d1b3cf18001ebcaa383aed773fa553d52a793dc4e826cf10ddb4fe32e9913</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4009,27902,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8103097$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3028580$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sharkey, Mary Ann</creatorcontrib><creatorcontrib>Steedman, John G.</creatorcontrib><creatorcontrib>Lund, Raymond D.</creatorcontrib><creatorcontrib>Dom, Richard M.</creatorcontrib><title>Tectal transplants into the occipital cortex of the newborn rat</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>Embryonic day 15 rostral tectum (presumptive superior colliculus) was transplanted into the occipital cortex of newborn rats. One to two months later, the transplants were visualized and injected with either horseradish peroxidase (HRP) or wheat germ agglutinin conjugated with HRP (WGA/HRP). After the appropriate survival time and processing with either diaminobenzidine (DAB) or tetramethylbenzidine tetrahydrochloride (TMB), HRP-labelled pyramidal cells were found in layer V of the host ipsilateral occipital cortex. Thus, the occipitotectal connections are formed between host and graft despite the fact that the fibers must grow in a direction opposite to their normal course to reach the aberrantly positioned tectal graft.</description><subject>Animals</subject><subject>Animals, Newborn - physiology</subject><subject>Biological and medical sciences</subject><subject>Connectional selectivity</subject><subject>Eye and associated structures. Visual pathways and centers. Vision</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Horseradish Peroxidase</subject><subject>Layer V</subject><subject>Nerve Fibers - physiology</subject><subject>Neural Pathways - physiology</subject><subject>Occipital cortex</subject><subject>Occipital Lobe - physiology</subject><subject>Occipital Lobe - surgery</subject><subject>Pyramidal cell</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Synaptic Transmission</subject><subject>Tectum</subject><subject>Tectum Mesencephali - physiology</subject><subject>Tectum Mesencephali - transplantation</subject><subject>Transplantation</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0165-3806</issn><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAURYMo4zj6DxS6ENFFNWmaNt0oMvgFA27GdUiTV4x0mppk_Pj3pjNlli7Cg9zzHpeD0CnB1wST4iY-llKOi0teXlUYc56yPTQlvMzSIsvxPprukEN05P0HxphQTiZoQnHGGcdTdLcEFWSbBCc737eyCz4xXbBJeIfEKmV6M8TKugA_iW02_x1819Z1iZPhGB00svVwMs4Zent8WM6f08Xr08v8fpGqnOUhZaSoNKmpagiPJaBWUlJOJeiypI1kjGqWybKiWuXAsyJyWOs6b4BmUFWEztDF9m7v7OcafBAr4xW0sTHYtRfxDC8Y4xHMt6By1nsHjeidWUn3KwgWgzcxSBGDFMFLsfEmWFw7G--v6xXo3dIoKubnYy69km0TdSnjdxgnmOKqjNjtFoPo4suAE14Z6BRo46Jooa35v8cf0ruI-g</recordid><startdate>1987</startdate><enddate>1987</enddate><creator>Sharkey, Mary Ann</creator><creator>Steedman, John G.</creator><creator>Lund, Raymond D.</creator><creator>Dom, Richard M.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1987</creationdate><title>Tectal transplants into the occipital cortex of the newborn rat</title><author>Sharkey, Mary Ann ; Steedman, John G. ; Lund, Raymond D. ; Dom, Richard M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c454t-5169d1b3cf18001ebcaa383aed773fa553d52a793dc4e826cf10ddb4fe32e9913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Animals</topic><topic>Animals, Newborn - physiology</topic><topic>Biological and medical sciences</topic><topic>Connectional selectivity</topic><topic>Eye and associated structures. Visual pathways and centers. Vision</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Horseradish Peroxidase</topic><topic>Layer V</topic><topic>Nerve Fibers - physiology</topic><topic>Neural Pathways - physiology</topic><topic>Occipital cortex</topic><topic>Occipital Lobe - physiology</topic><topic>Occipital Lobe - surgery</topic><topic>Pyramidal cell</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Synaptic Transmission</topic><topic>Tectum</topic><topic>Tectum Mesencephali - physiology</topic><topic>Tectum Mesencephali - transplantation</topic><topic>Transplantation</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sharkey, Mary Ann</creatorcontrib><creatorcontrib>Steedman, John G.</creatorcontrib><creatorcontrib>Lund, Raymond D.</creatorcontrib><creatorcontrib>Dom, Richard M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sharkey, Mary Ann</au><au>Steedman, John G.</au><au>Lund, Raymond D.</au><au>Dom, Richard M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tectal transplants into the occipital cortex of the newborn rat</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>1987</date><risdate>1987</risdate><volume>31</volume><issue>1</issue><spage>119</spage><epage>123</epage><pages>119-123</pages><issn>0165-3806</issn><issn>0006-8993</issn><eissn>1872-6240</eissn><coden>BRREAP</coden><abstract>Embryonic day 15 rostral tectum (presumptive superior colliculus) was transplanted into the occipital cortex of newborn rats. One to two months later, the transplants were visualized and injected with either horseradish peroxidase (HRP) or wheat germ agglutinin conjugated with HRP (WGA/HRP). After the appropriate survival time and processing with either diaminobenzidine (DAB) or tetramethylbenzidine tetrahydrochloride (TMB), HRP-labelled pyramidal cells were found in layer V of the host ipsilateral occipital cortex. Thus, the occipitotectal connections are formed between host and graft despite the fact that the fibers must grow in a direction opposite to their normal course to reach the aberrantly positioned tectal graft.</abstract><cop>London</cop><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier B.V</pub><pmid>3028580</pmid><doi>10.1016/0165-3806(87)90088-5</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0165-3806 |
| ispartof | Brain research, 1987, Vol.31 (1), p.119-123 |
| issn | 0165-3806 0006-8993 1872-6240 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77386558 |
| source | MEDLINE; Elsevier ScienceDirect Journals; Alma/SFX Local Collection |
| subjects | Animals Animals, Newborn - physiology Biological and medical sciences Connectional selectivity Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology Horseradish Peroxidase Layer V Nerve Fibers - physiology Neural Pathways - physiology Occipital cortex Occipital Lobe - physiology Occipital Lobe - surgery Pyramidal cell Rats Rats, Inbred Strains Synaptic Transmission Tectum Tectum Mesencephali - physiology Tectum Mesencephali - transplantation Transplantation Vertebrates: nervous system and sense organs |
| title | Tectal transplants into the occipital cortex of the newborn rat |
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