Transchromosomally derived Ig heavy chains

During an immune response, activated B cells undergo isotype switching and begin to express isotypes other than IgM and IgD. Isotype switching occurs when downstream C gamma, C alpha, or C epsilon genes are rearranged into the S mu chromosomal region, resulting in the deletion of the region in betwe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 1995-07, Vol.155 (2), p.684-691
Hauptverfasser:	Knight, KL, Kingzette, M, Crane, MA, Zhai, SK
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Cloning, Molecular DNA, Complementary - analysis Gene Rearrangement - genetics Haplotypes Immunoglobulin A - genetics Immunoglobulin Class Switching - genetics Immunoglobulin Heavy Chains - genetics Molecular Sequence Data Polymorphism, Genetic - genetics Rabbits RNA, Messenger - analysis RNA, Messenger - genetics Translocation, Genetic - genetics
Online-Zugang:	Volltext
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