Is caloric restriction effective in preventing diabetes mellitus in the Otsuka Long Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus?

Studies were made on the effectiveness of caloric restriction in preventing the development of diabetes mellitus in a model rat (Otsuka-Long-Evans-Tokushima Fatty; OLETF) with non-insulin-dependent diabetes mellitus (NIDDM). Groups of 8 male OLETF rats aged 5 weeks were supplied with rat chow ad lib...

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Veröffentlicht in:	Diabetes research and clinical practice 1995-02, Vol.27 (2), p.97-106
Hauptverfasser:	Okauchi, Noriko, Mizuno, Akira, Yoshimoto, Sachiko, Zhu, Min, Sano, Toshiaki, Shima, Kenji
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal fat Aging - physiology Animals Biological and medical sciences Blood Glucose - metabolism Body Composition Body Weight Caloric restriction Cell Membrane - metabolism Diabetes Mellitus - genetics Diabetes Mellitus - physiopathology Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - physiopathology Diabetes Mellitus, Type 2 - prevention & control Diabetes. Impaired glucose tolerance Diet, Reducing Endocrine pancreas. Apud cells (diseases) Endocrinopathies Energy Intake Etiopathogenesis. Screening. Investigations. Target tissue resistance Glucose Clamp Technique Glucose Tolerance Test Glucose Transporter Type 4 Insulin resistance Intracellular Membranes - metabolism Islets of Langerhans - cytology Islets of Langerhans - pathology Male Medical sciences Monosaccharide Transport Proteins - metabolism Muscle Proteins Muscle, Skeletal - metabolism Non-insulin-dependent diabetes mellitus Obesity Rats Rats, Mutant Strains
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