A YAC contig containing the reeler locus with preliminary characterization of candidate gene fragments

The reeler mutation in the mouse maps to proximal chromosome 5 and defines a key gene involved in brain development and evolution. No gene product is known, and the locus is currently being characterized by positional cloning. YAC clones corresponding to the closest markers D5Mit61 and D5Mit72 have...

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Veröffentlicht in:	Genomics 1995-04, Vol.26 (3), p.543-549
Hauptverfasser:	Bar, I., De Rouvroit, C.Lambert, Royaux, I., Krizman, D.B., Dernoncourt, C., Ruelle, D., Beckers, M.C., Goffinet, A.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences BIOLOGICAL MARKERS BIOLOGY AND MEDICINE, BASIC STUDIES Cell Adhesion Molecules, Neuronal - genetics Chromosome Mapping CHROMOSOMES Chromosomes, Artificial, Yeast CONTIGS DESIGN DNA Primers DNA-CLONING ELECTROPHORESIS Extracellular Matrix Proteins - genetics Fundamental and applied biological sciences. Psychology GENE MUTATIONS GENES Genes. Genome GENETIC MAPPING MICE Mice, Inbred BALB C Molecular and cellular biology Molecular genetics Molecular Sequence Data Nerve Tissue Proteins - genetics PROBES Restriction Mapping RNA, Messenger - genetics Sequence Deletion Serine Endopeptidases TRANSCRIPTION YEASTS
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