Real‐Time Monitoring of Antigen‐antibody Recognition on a Metal Oxide Surface by an Optical Grating Coupler Sensor

Real‐time monitoring of intermolecular interactions can provide a direct and rapid estimate of the affinity and kinetics of interactions between biomolecules. Optical methods based on the measurement of changes of refractive index in the immediate vicinity of a liquid‐solid interface are particularl...

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Veröffentlicht in:	European journal of biochemistry 1995-06, Vol.230 (2), p.416-423
Hauptverfasser:	Bernard, André, Bosshard, Hans Rudolf
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antibodies, Monoclonal - chemistry Antigen-Antibody Reactions antigen‐antibody recognition Avidin - chemistry Biosensing Techniques biosensor Biotin - chemistry Grating coupler sensor Immunoglobulin G - chemistry Kinetics leucine zipper Metals Microscopy, Atomic Force Models, Theoretical Molecular Sequence Data Optics and Photonics Oxides Staphylococcal Protein A - chemistry surface plasmon resonance
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