Amyloid $\beta $ Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage near the Alzheimer Locus

The amyloid $\beta $ protein has been identified as an important component of both cerebrovascular amyloid and amyloid plaques of Alzheimer's disease and Down syndrome. A complementary DNA for the $\beta $ protein suggests that it derives from a larger protein expressed in a variety of tissues....

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1987-02, Vol.235 (4791), p.880-884
Hauptverfasser: Tanzi, Rudolph E., Gusella, James F., Watkins, Paul C., Gail A. P. Bruns, St George-Hyslop, Peter, Van Keuren, Margaret L., Patterson, David, Pagan, Susan, Kurnit, David M., Neve, Rachael L.
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Sprache:eng
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