Evaluation of models for analysis of radioligand binding data

In the presence of agonists, many neurotransmitter receptors interact with regulatory components, resulting in the formation of a ternary complex composed of agonist, receptor, and a regulatory component, and in biphasic or shallow dose response curves for inhibition of the binding of a radiolabeled...

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Veröffentlicht in:	Molecular pharmacology 1987-01, Vol.31 (1), p.103-111
Hauptverfasser:	ABRAMSON, S. N, MCGONIGLE, P, MOLINOFF, P. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - physiology Biological and medical sciences Computer Simulation General pharmacology GTP-Binding Proteins - physiology Kinetics Medical sciences Models, Theoretical Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments Radioligand Assay Receptors, Cell Surface - physiology
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