Primary adrenocortical carcinoma: CT evaluation with clinical correlation

Clinical histories and CT findings were reviewed in 38 patients with primary adrenocortical carcinomas. The primary tumors exhibited central areas of low attenuation representing tumor necrosis (n = 26), irregular contrast enhancement (n = 16), detectable calcification (n = 9), and a thin, capsuleli...

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Veröffentlicht in:American journal of roentgenology (1976) 1987-03, Vol.148 (3), p.531-535
Hauptverfasser: Fishman, EK, Deutch, BM, Hartman, DS, Goldman, SM, Zerhouni, EA, Siegelman, SS
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container_end_page 535
container_issue 3
container_start_page 531
container_title American journal of roentgenology (1976)
container_volume 148
creator Fishman, EK
Deutch, BM
Hartman, DS
Goldman, SM
Zerhouni, EA
Siegelman, SS
description Clinical histories and CT findings were reviewed in 38 patients with primary adrenocortical carcinomas. The primary tumors exhibited central areas of low attenuation representing tumor necrosis (n = 26), irregular contrast enhancement (n = 16), detectable calcification (n = 9), and a thin, capsulelike rim surrounding the tumor (n = 7). Tumors metastasized to liver (n = 9), lung (n = 5), and lymph nodes (n = 5). In eight of nine cases of liver metastasis the primary tumor arose in the left adrenal gland. Evidence of endocrinopathy was present in each of nine patients with lesions 6 cm or less in diameter, but in only two of seven adults with lesions exceeding 15 cm in diameter. We conclude that, contrary to established concepts, adrenocortical carcinoma may present as a smooth, homogeneous, functioning mass 6 cm or less in diameter on CT.
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source American Roentgen Ray Society; MEDLINE; Alma/SFX Local Collection
subjects Adrenal Gland Neoplasms - diagnostic imaging
Adult
Aged
Biological and medical sciences
Carcinoma - diagnostic imaging
Child
Endocrine glands
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Tomography, X-Ray Computed
title Primary adrenocortical carcinoma: CT evaluation with clinical correlation
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