Primary adrenocortical carcinoma: CT evaluation with clinical correlation
Clinical histories and CT findings were reviewed in 38 patients with primary adrenocortical carcinomas. The primary tumors exhibited central areas of low attenuation representing tumor necrosis (n = 26), irregular contrast enhancement (n = 16), detectable calcification (n = 9), and a thin, capsuleli...
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Veröffentlicht in: | American journal of roentgenology (1976) 1987-03, Vol.148 (3), p.531-535 |
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container_title | American journal of roentgenology (1976) |
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creator | Fishman, EK Deutch, BM Hartman, DS Goldman, SM Zerhouni, EA Siegelman, SS |
description | Clinical histories and CT findings were reviewed in 38 patients with primary adrenocortical carcinomas. The primary tumors exhibited central areas of low attenuation representing tumor necrosis (n = 26), irregular contrast enhancement (n = 16), detectable calcification (n = 9), and a thin, capsulelike rim surrounding the tumor (n = 7). Tumors metastasized to liver (n = 9), lung (n = 5), and lymph nodes (n = 5). In eight of nine cases of liver metastasis the primary tumor arose in the left adrenal gland. Evidence of endocrinopathy was present in each of nine patients with lesions 6 cm or less in diameter, but in only two of seven adults with lesions exceeding 15 cm in diameter. We conclude that, contrary to established concepts, adrenocortical carcinoma may present as a smooth, homogeneous, functioning mass 6 cm or less in diameter on CT. |
doi_str_mv | 10.2214/ajr.148.3.531 |
format | Article |
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The primary tumors exhibited central areas of low attenuation representing tumor necrosis (n = 26), irregular contrast enhancement (n = 16), detectable calcification (n = 9), and a thin, capsulelike rim surrounding the tumor (n = 7). Tumors metastasized to liver (n = 9), lung (n = 5), and lymph nodes (n = 5). In eight of nine cases of liver metastasis the primary tumor arose in the left adrenal gland. Evidence of endocrinopathy was present in each of nine patients with lesions 6 cm or less in diameter, but in only two of seven adults with lesions exceeding 15 cm in diameter. We conclude that, contrary to established concepts, adrenocortical carcinoma may present as a smooth, homogeneous, functioning mass 6 cm or less in diameter on CT.</description><identifier>ISSN: 0361-803X</identifier><identifier>EISSN: 1546-3141</identifier><identifier>DOI: 10.2214/ajr.148.3.531</identifier><identifier>PMID: 3492881</identifier><identifier>CODEN: AAJRDX</identifier><language>eng</language><publisher>Leesburg, VA: Am Roentgen Ray Soc</publisher><subject>Adrenal Gland Neoplasms - diagnostic imaging ; Adult ; Aged ; Biological and medical sciences ; Carcinoma - diagnostic imaging ; Child ; Endocrine glands ; Female ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical sciences ; Middle Aged ; Radiodiagnosis. Nmr imagery. Nmr spectrometry ; Tomography, X-Ray Computed</subject><ispartof>American journal of roentgenology (1976), 1987-03, Vol.148 (3), p.531-535</ispartof><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-96b8eaefe55a17343b851db76b91abbf4360d7dca0251aa567fb04feeae5dc963</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,776,780,785,786,4106,23909,23910,25118,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8208542$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3492881$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fishman, EK</creatorcontrib><creatorcontrib>Deutch, BM</creatorcontrib><creatorcontrib>Hartman, DS</creatorcontrib><creatorcontrib>Goldman, SM</creatorcontrib><creatorcontrib>Zerhouni, EA</creatorcontrib><creatorcontrib>Siegelman, SS</creatorcontrib><title>Primary adrenocortical carcinoma: CT evaluation with clinical correlation</title><title>American journal of roentgenology (1976)</title><addtitle>AJR Am J Roentgenol</addtitle><description>Clinical histories and CT findings were reviewed in 38 patients with primary adrenocortical carcinomas. The primary tumors exhibited central areas of low attenuation representing tumor necrosis (n = 26), irregular contrast enhancement (n = 16), detectable calcification (n = 9), and a thin, capsulelike rim surrounding the tumor (n = 7). Tumors metastasized to liver (n = 9), lung (n = 5), and lymph nodes (n = 5). In eight of nine cases of liver metastasis the primary tumor arose in the left adrenal gland. Evidence of endocrinopathy was present in each of nine patients with lesions 6 cm or less in diameter, but in only two of seven adults with lesions exceeding 15 cm in diameter. We conclude that, contrary to established concepts, adrenocortical carcinoma may present as a smooth, homogeneous, functioning mass 6 cm or less in diameter on CT.</description><subject>Adrenal Gland Neoplasms - diagnostic imaging</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Carcinoma - diagnostic imaging</subject><subject>Child</subject><subject>Endocrine glands</subject><subject>Female</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Tomography, X-Ray Computed</subject><issn>0361-803X</issn><issn>1546-3141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1LxDAQhoMoun4cPQo9iLeumSZpUm-y-AWCHhS8hWmaupG01aRr8d8b3UVPObzPvJN5CDkGOi8K4Of4FubA1ZzNBYMtMgPBy5wBh20yo6yEXFH2skf2Y3yjlEpVyV2yy3hVKAUzcvcYXIfhK8Mm2H4wQxidQZ8ZDMb1Q4cX2eIps5_oVzi6oc8mNy4z412_xoYQrP9NDslOiz7ao817QJ6vr54Wt_n9w83d4vI-N0zJMa_KWlm0rRUCQTLOaiWgqWVZV4B13XJW0kY2BmkhAFGUsq0pb22aEY2pSnZAzta972H4WNk46s5FY73H3g6rqKVkCqDkCczXoAlDjMG2-n19qwaqf9TppE4ndZrppC7xJ5viVd3Z5o_euEr56SbHmG5vA_bGxT9MFVQJXvz_b-lel5MLVscOvU-loKdp-t_3DQkJhWg</recordid><startdate>19870301</startdate><enddate>19870301</enddate><creator>Fishman, EK</creator><creator>Deutch, BM</creator><creator>Hartman, DS</creator><creator>Goldman, SM</creator><creator>Zerhouni, EA</creator><creator>Siegelman, SS</creator><general>Am Roentgen Ray Soc</general><general>American Roentgen Ray Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19870301</creationdate><title>Primary adrenocortical carcinoma: CT evaluation with clinical correlation</title><author>Fishman, EK ; Deutch, BM ; Hartman, DS ; Goldman, SM ; Zerhouni, EA ; Siegelman, SS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-96b8eaefe55a17343b851db76b91abbf4360d7dca0251aa567fb04feeae5dc963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Adrenal Gland Neoplasms - diagnostic imaging</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Carcinoma - diagnostic imaging</topic><topic>Child</topic><topic>Endocrine glands</topic><topic>Female</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fishman, EK</creatorcontrib><creatorcontrib>Deutch, BM</creatorcontrib><creatorcontrib>Hartman, DS</creatorcontrib><creatorcontrib>Goldman, SM</creatorcontrib><creatorcontrib>Zerhouni, EA</creatorcontrib><creatorcontrib>Siegelman, SS</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of roentgenology (1976)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fishman, EK</au><au>Deutch, BM</au><au>Hartman, DS</au><au>Goldman, SM</au><au>Zerhouni, EA</au><au>Siegelman, SS</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary adrenocortical carcinoma: CT evaluation with clinical correlation</atitle><jtitle>American journal of roentgenology (1976)</jtitle><addtitle>AJR Am J Roentgenol</addtitle><date>1987-03-01</date><risdate>1987</risdate><volume>148</volume><issue>3</issue><spage>531</spage><epage>535</epage><pages>531-535</pages><issn>0361-803X</issn><eissn>1546-3141</eissn><coden>AAJRDX</coden><abstract>Clinical histories and CT findings were reviewed in 38 patients with primary adrenocortical carcinomas. The primary tumors exhibited central areas of low attenuation representing tumor necrosis (n = 26), irregular contrast enhancement (n = 16), detectable calcification (n = 9), and a thin, capsulelike rim surrounding the tumor (n = 7). Tumors metastasized to liver (n = 9), lung (n = 5), and lymph nodes (n = 5). In eight of nine cases of liver metastasis the primary tumor arose in the left adrenal gland. Evidence of endocrinopathy was present in each of nine patients with lesions 6 cm or less in diameter, but in only two of seven adults with lesions exceeding 15 cm in diameter. We conclude that, contrary to established concepts, adrenocortical carcinoma may present as a smooth, homogeneous, functioning mass 6 cm or less in diameter on CT.</abstract><cop>Leesburg, VA</cop><pub>Am Roentgen Ray Soc</pub><pmid>3492881</pmid><doi>10.2214/ajr.148.3.531</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adrenal Gland Neoplasms - diagnostic imaging Adult Aged Biological and medical sciences Carcinoma - diagnostic imaging Child Endocrine glands Female Humans Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Radiodiagnosis. Nmr imagery. Nmr spectrometry Tomography, X-Ray Computed |
title | Primary adrenocortical carcinoma: CT evaluation with clinical correlation |
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