Pharmacokinetics of 99mTc(Sn)- and 131I-labeled anti-carcinoembryonic antigen monoclonal antibody fragments in nude mice

The biodistribution, radioimmunoimaging, and high pressure liquid chromatography activity profiles of 99mTc(Sn) and 131I-labeled anti-carcinoembryonic antigen monoclonal antibody fragments were compared. Nude mice, bearing specific (colon carcinoma, LS174T) and nonspecific (pancreatic carcinoma, MIA...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1987-03, Vol.47 (6), p.1691-1694
Hauptverfasser:	ZIMMER, A. M, KAZIKIEWICZ, J. M, ROSEN, S. T, SPIES, S. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Biological and medical sciences Carcinoembryonic Antigen - immunology Immunoglobulin Fab Fragments Investigative techniques, diagnostic techniques (general aspects) Iodine Radioisotopes Kidney - diagnostic imaging Kinetics Medical sciences Mice Mice, Inbred BALB C Mice, Nude Radionuclide Imaging Radionuclide investigations Technetium Technetium Compounds Tin Tin Compounds
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