Brefeldin a inhibits the transcytotic vesicular transport of horseradish peroxidase in intrahepatic bile ductules isolated from rat liver

The fungal metabolite Brefeldin A (BFA) has become a valuable tool to address mechanisms of membrane transport in eukaryotic cells. The aim of the study was to investigate the action of BFA on the endocytic and transcytotic pathways in the biliary epithelium. Intrahepatic bile ductules were isolated...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 1995-07, Vol.22 (1), p.194-201
Hauptverfasser:	Benedetti, Antonio, Marucci, Luca, Bassotti, Cristina, Guidarelli, Carlo, Jezequel, Anne Marie
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bile Ducts, Intrahepatic - metabolism Biological and medical sciences Biological Transport - drug effects Brefeldin A Cyclopentanes - pharmacology Fundamental and applied biological sciences. Psychology Horseradish Peroxidase - pharmacokinetics In Vitro Techniques Liver. Bile. Biliary tracts Male Rats Rats, Sprague-Dawley Taurocholic Acid - pharmacology Thiamine Pyrophosphatase - metabolism Tissue Distribution Vertebrates: digestive system
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