Effect of GABA and benzodiazepines on testicular androgen production

We have evaluated the effect of R05-4864, a selective probe to label peripheral type benzodiazepine receptor, on “in vitro” testicular androgen production. Decapsulated testes from adult rats showed a significant increase in the basal and hCG-stimulated testosterone secretion into the medium in resp...

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Veröffentlicht in:	Life sciences (1973) 1987-02, Vol.40 (8), p.791-798
Hauptverfasser:	Ritta, Mónica N., Campos, María B., Calandra, Ricardo S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Androgens - biosynthesis Animals Benzodiazepinones - pharmacology Chorionic Gonadotropin - pharmacology gamma-Aminobutyric Acid - metabolism gamma-Aminobutyric Acid - pharmacology Male Rats Receptors, GABA-A - drug effects Sexual Maturation Testis - drug effects Testis - metabolism
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