UV Light as a Footprinting Agent: Modulation of UV-induced DNA Damage by Transcription Factors Bound at the Promoters of Three Human Genes

Protein-DNA interactions in mammalian cells can be analyzed at the nucleotide level of resolution by genomic sequencing techniques. The most sensitive genomic sequencing method uses the ligation-mediated polymerase chain reaction (LMPCR) for signal amplification to detect the position of DNA modific...

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