The role of phospholipase A activity in rat liver microsomal lipid peroxidation

The involvement of phospholipase(s) A in lipid peroxidation of rat liver microsomes was investigated by: (a) determining the effects of phospholipase A inhibitors (p-bromophenylacyl bromide, chlorpromazine, mepacrine) on the accumulation of thiobarbituric acid reactivity or on levels of oxidized pho...

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Veröffentlicht in:	The Journal of biological chemistry 1987-02, Vol.262 (4), p.1479-1484
Hauptverfasser:	Beckman, J K, Borowitz, S M, Burr, I M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetophenones - pharmacology Adenosine Diphosphate - metabolism Alloxan - pharmacology Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Chlorpromazine - pharmacology Copper - pharmacology Ferrous Compounds - pharmacology Fundamental and applied biological sciences. Psychology Glutathione - metabolism Hydrogen-Ion Concentration Lipid Peroxides - metabolism Lipids Male Microsomes, Liver - drug effects Microsomes, Liver - enzymology Other biological molecules Phospholipases - metabolism Phospholipases A - metabolism Phospholipases A1 Phospholipases A2 Quinacrine - pharmacology Rats Rats, Inbred Strains
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