Population pharmacokinetics of alfentanil: the average dose-plasma concentration relationship and interindividual variability in patients

The population pharmacokinetic parameters describing the plasma concentration versus time profile of alfentanil in patients undergoing general anesthesia were determined from 614 plasma concentration measurements collected in four previously reported studies with a total of 45 patients. A nonlinear...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 1987, Vol.66 (1), p.3-12
Hauptverfasser:	MAITRE, P. O, VOZEH, S, HEYKANTS, J, THOMSON, D. A, STANSKI, D. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alfentanil Anesthesia, General Anesthetics. Neuromuscular blocking agents Biological and medical sciences Body Weight Female Fentanyl - analogs & derivatives Fentanyl - blood Humans Kinetics Male Mathematics Medical sciences Neuropharmacology Pharmacology. Drug treatments Sex Factors
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