A giant nucleopore protein that binds Ran/TC4

RAN/TC4 is a small nuclear G protein 1 that forms a complex with the chromatin-bound guanine nucleotide release factor RCC1 (ref. 2). Loss of RCC1 causes defects in cell cycle progression 3,4 , RNA export 5-7 and nuclear protein import 8 . Some of these can be suppressed by overexpression of Ran/TC4...

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Veröffentlicht in:	Nature (London) 1995-07, Vol.376 (6536), p.184-188
Hauptverfasser:	Yokoyama, N., Hayashi, N., Seki, T., Panté, N., Ohba, T., Nishii, K., Kuma, K., Hayashida, T., Miyata, T., Aebi, U., Fukui, M., Nishimoto, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Base Sequence Binding and carrier proteins Biological and medical sciences Biological Transport Blotting, Northern cDNA Cloning, Molecular DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Escherichia coli Fundamental and applied biological sciences. Psychology HeLa Cells Humanities and Social Sciences Humans letter man Molecular biology Molecular Chaperones Molecular Sequence Data multidisciplinary Neurology Nuclear Envelope - metabolism Nuclear Pore Complex Proteins nuclear pores Nuclear Proteins - genetics Nuclear Proteins - metabolism nucleotide sequence Protein Binding protein import Proteins ran GTP-Binding Protein Ran/TC4 protein RanBP2 protein Rats Recombinant Proteins - metabolism Science Science (multidisciplinary) Sequence Homology, Amino Acid Tumor Cells, Cultured Zinc Fingers - genetics
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