Physico-mechanical characterization of the extrusion-spheronization process. Part II: Rheological determinants for successful extrusion and spheronization

Spheres are widely used as the basis for the design of multiparticulate drug delivery systems. Although the extrusion and spheronization processes are frequently used to produce such spheres, there is a lack of basic understanding of these processes and of the requisite properties of excipients and...

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Veröffentlicht in:	Pharmaceutical research 1995-04, Vol.12 (4), p.496-507
Hauptverfasser:	Shah, R D, Kabadi, M, Pope, D G, Augsburger, L L
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug Delivery Systems Regression Analysis Technology, Pharmaceutical Tensile Strength
Online-Zugang:	Volltext
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