Transduction of chemostimuli by the type I carotid body cell

The postulated mechanisms for hypoxic and acidic chemotransduction by type I cells that we have described here are summarized in the diagrams of Fig. 4. Most if not all of these require more complete evaluation and, as we have described, there are obvious points of contention that need to be resolve...

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Veröffentlicht in:	The Journal of membrane biology 1995-03, Vol.144 (1), p.1-9
Hauptverfasser:	Peers, C, Buckler, K J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carotid Body - cytology Carotid Body - physiology Chemoreceptor Cells - physiology Hydrogen-Ion Concentration Hypercapnia - physiopathology Hypoxia - physiopathology Neurotransmitter Agents - physiology Potassium Channels - physiology Rabbits Rats Respiration - physiology Space life sciences
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creator	Peers, C Buckler, K J
description	The postulated mechanisms for hypoxic and acidic chemotransduction by type I cells that we have described here are summarized in the diagrams of Fig. 4. Most if not all of these require more complete evaluation and, as we have described, there are obvious points of contention that need to be resolved. Nevertheless, it is apparent that studies of isolated type I cell preparations carried out over the last six years have provided significant advancements in our understanding of chemotransduction in the type I cell. Only when the functioning of these cells has been fully described can we hope to understand the mechanisms underlying the responses of the intact organ to chemostimuli.
doi_str_mv	10.1007/bf00238411
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subjects	Animals Carotid Body - cytology Carotid Body - physiology Chemoreceptor Cells - physiology Hydrogen-Ion Concentration Hypercapnia - physiopathology Hypoxia - physiopathology Neurotransmitter Agents - physiology Potassium Channels - physiology Rabbits Rats Respiration - physiology Space life sciences
title	Transduction of chemostimuli by the type I carotid body cell
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