Site-selected introduction of modified purine and pyrimidine ribonucleosides into RNA by automated phosphoramidite chemistry

The study of modified nucleoside contributions to RNA chemistry, structure and function has been hwarted by the lack of a site-selected method of incorporation which is both versatile and adaptable to present synthetic technologies. A reproducible and versatile site-selected incorporation of nine di...

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Veröffentlicht in:	Biochimie 1995, Vol.77 (1), p.125-134
Hauptverfasser:	Agris, P.F., Malkiewicz, A., Kraszewski, A., Everett, K., Nawrot, B., Sochacka, E., Jankowska, J., Guenther, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides Anticodon - chemistry Anticodon - genetics automated chemical synthesis Base Sequence Escherichia coli Magnetic Resonance Spectroscopy modified nucleosides Molecular Sequence Data Nucleic Acid Conformation Phosphoramides phosphoramidite chemistry Phosphoric Acids Purines - chemical synthesis Purines - chemistry Pyrimidines - chemical synthesis Pyrimidines - chemistry Ribonucleosides - chemical synthesis Ribonucleosides - chemistry Ribonucleosides - isolation & purification RNA Processing, Post-Transcriptional - genetics RNA, Transfer, Glu - chemical synthesis RNA, Transfer, Glu - chemistry RNA, Transfer, Phe - chemical synthesis RNA, Transfer, Phe - chemistry site-selected incorporation
Online-Zugang:	Volltext
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