Nitric Oxide (NO) Donor Molecules: Effect of NO Release Rate on Vascular Smooth Muscle Cell Proliferation In Vitro

Nitric oxide (NO) inhibits vascular smooth muscle cell (SMC) growth in vitro. To determine the effects of release rate and exposure time on SMC growth inhibition by NO, we compared the activities of five NO donors that generate NO with half-lives of 2 min (DEA/NO, Et2N[N2O2]Na), 15 min (PAPA/NO, CH3...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1995-04, Vol.25 (4), p.674-678
Hauptverfasser:	Mooradian, Daniel L, Hutsell, Thomas C, Keefer, Larry K
Format:	Artikel
Sprache:	eng
Schlagworte:	Angioplasty, Balloon Animals Biological and medical sciences Cardiovascular system Cell Division - physiology Cells, Cultured DNA - biosynthesis Half-Life Hyperplasia - pathology Medical sciences Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - pathology Nitric Oxide - metabolism Nitric Oxide - physiology Pharmacology. Drug treatments Rats Vascular wall
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