Usefulness of Endothelin-1 as a Predictor of Response to Head-Up Tilt-Table Testing in Children With Syncope
Recurrent syncope in children and adolescents is a frequently encountered problem in the practice of pediatrics. The etiology of syncope in otherwise healthy persons is considered as a neurally mediated vasovagal reaction. It is postulated that neurally mediated syncope occurs during rapid or prolon...
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| Veröffentlicht in: | The American journal of cardiology 1995-07, Vol.76 (1-2), p.86-88 |
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| container_title | The American journal of cardiology |
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| creator | Mehta, Mary Wolff, Grace Young, Ming-Lon Mas, Madeleen S. Escobar, Amelia Gelband, Henry |
| description | Recurrent syncope in children and adolescents is a frequently encountered problem in the practice of pediatrics. The etiology of syncope in otherwise healthy persons is considered as a neurally mediated vasovagal reaction. It is postulated that neurally mediated syncope occurs during rapid or prolonged upright positioning. This results in decreased preload, increased ventricular contraction, and sudden activation of cardiac mechanoreceptors by way of the afferent unmyelinated C-fibers.l This causes central sympathetic withdrawal and vagal enhancement, thereby promoting vasodilatation, bradycardia and decreased cerebral perfusion, and syncope. |
| doi_str_mv | 10.1016/S0002-9149(99)80810-8 |
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The etiology of syncope in otherwise healthy persons is considered as a neurally mediated vasovagal reaction. It is postulated that neurally mediated syncope occurs during rapid or prolonged upright positioning. This results in decreased preload, increased ventricular contraction, and sudden activation of cardiac mechanoreceptors by way of the afferent unmyelinated C-fibers.l This causes central sympathetic withdrawal and vagal enhancement, thereby promoting vasodilatation, bradycardia and decreased cerebral perfusion, and syncope.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/S0002-9149(99)80810-8</identifier><identifier>PMID: 7793414</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adolescent ; Biochemistry ; Biological and medical sciences ; Blood pressure ; Bradycardia ; Cardiovascular disease ; Case-Control Studies ; Child ; Children ; Children & youth ; Contraction ; Endothelin 1 ; Endothelins ; Endothelins - physiology ; Etiology ; Female ; Fibers ; Humans ; Male ; Mechanoreceptors ; Medical research ; Medical sciences ; Nervous system (semeiology, syndromes) ; Nervous system as a whole ; Neurology ; Patients ; Pediatrics ; Perfusion ; Posture ; Predictive Value of Tests ; Prospective Studies ; Sensory neurons ; Syncope ; Syncope - physiopathology ; Tilt-Table Test ; Vagus nerve ; Variance analysis ; Vasodilation ; Ventricle</subject><ispartof>The American journal of cardiology, 1995-07, Vol.76 (1-2), p.86-88</ispartof><rights>1995 Elsevier Inc.</rights><rights>1995 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. 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The etiology of syncope in otherwise healthy persons is considered as a neurally mediated vasovagal reaction. It is postulated that neurally mediated syncope occurs during rapid or prolonged upright positioning. This results in decreased preload, increased ventricular contraction, and sudden activation of cardiac mechanoreceptors by way of the afferent unmyelinated C-fibers.l This causes central sympathetic withdrawal and vagal enhancement, thereby promoting vasodilatation, bradycardia and decreased cerebral perfusion, and syncope.</description><subject>Adolescent</subject><subject>Biochemistry</subject><subject>Biological and medical sciences</subject><subject>Blood pressure</subject><subject>Bradycardia</subject><subject>Cardiovascular disease</subject><subject>Case-Control Studies</subject><subject>Child</subject><subject>Children</subject><subject>Children & youth</subject><subject>Contraction</subject><subject>Endothelin 1</subject><subject>Endothelins</subject><subject>Endothelins - physiology</subject><subject>Etiology</subject><subject>Female</subject><subject>Fibers</subject><subject>Humans</subject><subject>Male</subject><subject>Mechanoreceptors</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Nervous system as a whole</subject><subject>Neurology</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>Perfusion</subject><subject>Posture</subject><subject>Predictive Value of Tests</subject><subject>Prospective Studies</subject><subject>Sensory neurons</subject><subject>Syncope</subject><subject>Syncope - physiopathology</subject><subject>Tilt-Table Test</subject><subject>Vagus nerve</subject><subject>Variance analysis</subject><subject>Vasodilation</subject><subject>Ventricle</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkVFrFDEQx4Mo9ax-hEJQEX1YzWx2N5snkaNaoaDYO3wMuezES8kl22RX6Lc31zvuQRDJQwjzm5k_-RFyAew9MOg-3DDG6kpCI99K-a5nPbCqf0QW0AtZgQT-mCxOyFPyLOfb8gRouzNyJoTkDTQL4tcZ7ewD5kyjpZdhiNMWvQsVUJ2ppt8TDs5MMe3LPzCPMWSkU6RXqIdqPdKV81O10huPdIV5cuEXdYEut84PCQP96aYtvbkPJo74nDyx2md8cbzPyfrz5Wp5VV1_-_J1-em6Mo2EqZIWUBrRAK91W1tkMGCrhWZdz23NNO-6BvuNqblgVg7M8FaYTSfajoFtOOfn5M1h7pji3VxCqZ3LBr3XAeOclRC8hZ6xAr76C7yNcwolm6p5U45goivUy39TrCyXdV-g9gCZFHNOaNWY3E6newVM7YWpB2Fqb0NJqR6EqX3fxXH4vNnhcOo6Gir118e6zkZ7m3QwLp8w3sq-hrZgHw8Yln_97TCpbBwGU-QlNJMaovtPkD9Ak670</recordid><startdate>19950701</startdate><enddate>19950701</enddate><creator>Mehta, Mary</creator><creator>Wolff, Grace</creator><creator>Young, Ming-Lon</creator><creator>Mas, Madeleen S.</creator><creator>Escobar, Amelia</creator><creator>Gelband, Henry</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>19950701</creationdate><title>Usefulness of Endothelin-1 as a Predictor of Response to Head-Up Tilt-Table Testing in Children With Syncope</title><author>Mehta, Mary ; Wolff, Grace ; Young, Ming-Lon ; Mas, Madeleen S. ; Escobar, Amelia ; Gelband, Henry</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c491t-9f1e9c74132a52fe01de5a7a0683f20a3664e8bc2370f9d0c357cb675601f4333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Adolescent</topic><topic>Biochemistry</topic><topic>Biological and medical sciences</topic><topic>Blood pressure</topic><topic>Bradycardia</topic><topic>Cardiovascular disease</topic><topic>Case-Control Studies</topic><topic>Child</topic><topic>Children</topic><topic>Children & youth</topic><topic>Contraction</topic><topic>Endothelin 1</topic><topic>Endothelins</topic><topic>Endothelins - physiology</topic><topic>Etiology</topic><topic>Female</topic><topic>Fibers</topic><topic>Humans</topic><topic>Male</topic><topic>Mechanoreceptors</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Nervous system as a whole</topic><topic>Neurology</topic><topic>Patients</topic><topic>Pediatrics</topic><topic>Perfusion</topic><topic>Posture</topic><topic>Predictive Value of Tests</topic><topic>Prospective Studies</topic><topic>Sensory neurons</topic><topic>Syncope</topic><topic>Syncope - physiopathology</topic><topic>Tilt-Table Test</topic><topic>Vagus nerve</topic><topic>Variance analysis</topic><topic>Vasodilation</topic><topic>Ventricle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mehta, Mary</creatorcontrib><creatorcontrib>Wolff, Grace</creatorcontrib><creatorcontrib>Young, Ming-Lon</creatorcontrib><creatorcontrib>Mas, Madeleen S.</creatorcontrib><creatorcontrib>Escobar, Amelia</creatorcontrib><creatorcontrib>Gelband, Henry</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mehta, Mary</au><au>Wolff, Grace</au><au>Young, Ming-Lon</au><au>Mas, Madeleen S.</au><au>Escobar, Amelia</au><au>Gelband, Henry</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Usefulness of Endothelin-1 as a Predictor of Response to Head-Up Tilt-Table Testing in Children With Syncope</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>1995-07-01</date><risdate>1995</risdate><volume>76</volume><issue>1-2</issue><spage>86</spage><epage>88</epage><pages>86-88</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>Recurrent syncope in children and adolescents is a frequently encountered problem in the practice of pediatrics. The etiology of syncope in otherwise healthy persons is considered as a neurally mediated vasovagal reaction. It is postulated that neurally mediated syncope occurs during rapid or prolonged upright positioning. This results in decreased preload, increased ventricular contraction, and sudden activation of cardiac mechanoreceptors by way of the afferent unmyelinated C-fibers.l This causes central sympathetic withdrawal and vagal enhancement, thereby promoting vasodilatation, bradycardia and decreased cerebral perfusion, and syncope.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>7793414</pmid><doi>10.1016/S0002-9149(99)80810-8</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | The American journal of cardiology, 1995-07, Vol.76 (1-2), p.86-88 |
| issn | 0002-9149 1879-1913 |
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| subjects | Adolescent Biochemistry Biological and medical sciences Blood pressure Bradycardia Cardiovascular disease Case-Control Studies Child Children Children & youth Contraction Endothelin 1 Endothelins Endothelins - physiology Etiology Female Fibers Humans Male Mechanoreceptors Medical research Medical sciences Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Patients Pediatrics Perfusion Posture Predictive Value of Tests Prospective Studies Sensory neurons Syncope Syncope - physiopathology Tilt-Table Test Vagus nerve Variance analysis Vasodilation Ventricle |
| title | Usefulness of Endothelin-1 as a Predictor of Response to Head-Up Tilt-Table Testing in Children With Syncope |
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