Changes in preprotachykinin mRNA expression and substance P levels in dorsal root ganglia of monoarthritic rats: comparison with changes in synovial substance P levels

We have measured changes in the expression of γ-preprotachykinin mRNA and levels of the neuropeptide substance P in the lumbar 4 and 5 dorsal root ganglia at various time points following the induction of an antigenic monoarthritis in the rat knee. The results were compared with changes in substance...

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Veröffentlicht in:	Brain research 1995-03, Vol.675 (1), p.203-207
Hauptverfasser:	Garrett, Neil E., Kidd, Bruce L., Cruwys, Simon C., Tomlinson, David R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis, Experimental - metabolism Biological and medical sciences Blotting, Northern Diseases of the osteoarticular system Dorsal root ganglia Ganglia, Spinal - metabolism Inflammatory joint diseases Male Medical sciences Monoarthritis Preprotachykinin mRNA Protein Precursors - biosynthesis Rat Rats Rats, Wistar RNA, Messenger - biosynthesis Substance P Substance P - metabolism Synovial Fluid - metabolism Synovium Tachykinins - biosynthesis
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