Tubulointerstitial nephritis and uveitis : an immunological disorder ?
A 14-year-old boy with tubulointerstitial nephritis and uveitis (TINU syndrome) is described. Nephropathy improved without systemic cortisone treatment, whereas uveitis relapsed and was treated with topical steroids. Blood cell immunological analysis and serum analysis revealed signs of cytotoxic T-...
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| Veröffentlicht in: | Pediatric nephrology (Berlin, West) West), 1995-04, Vol.9 (2), p.193-195 |
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| container_end_page | 195 |
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| container_title | Pediatric nephrology (Berlin, West) |
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| creator | BIRNBACHER, R BALZAR, E AUFRICHT, C SCHMALDIENST, S WOLOSZCZUK, W FÖRSTER, E |
| description | A 14-year-old boy with tubulointerstitial nephritis and uveitis (TINU syndrome) is described. Nephropathy improved without systemic cortisone treatment, whereas uveitis relapsed and was treated with topical steroids. Blood cell immunological analysis and serum analysis revealed signs of cytotoxic T-cell, macrophage and granulocyte activation, which declined as the clinical symptoms improved. This may be interpreted as an indication of their significance as markers in the pathogenesis of this syndrome or as part of a microbial-triggered immune response. |
| doi_str_mv | 10.1007/BF00860744 |
| format | Article |
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Nephropathy improved without systemic cortisone treatment, whereas uveitis relapsed and was treated with topical steroids. Blood cell immunological analysis and serum analysis revealed signs of cytotoxic T-cell, macrophage and granulocyte activation, which declined as the clinical symptoms improved. This may be interpreted as an indication of their significance as markers in the pathogenesis of this syndrome or as part of a microbial-triggered immune response.</description><subject>Adolescent</subject><subject>Biological and medical sciences</subject><subject>Humans</subject><subject>Interstitial nephritis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nephritis, Interstitial - immunology</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Nephropathies. Renovascular diseases. 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Urinary tract diseases</topic><topic>Nephropathies. Renovascular diseases. Renal failure</topic><topic>Syndrome</topic><topic>Uveitis - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BIRNBACHER, R</creatorcontrib><creatorcontrib>BALZAR, E</creatorcontrib><creatorcontrib>AUFRICHT, C</creatorcontrib><creatorcontrib>SCHMALDIENST, S</creatorcontrib><creatorcontrib>WOLOSZCZUK, W</creatorcontrib><creatorcontrib>FÖRSTER, E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric nephrology (Berlin, West)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BIRNBACHER, R</au><au>BALZAR, E</au><au>AUFRICHT, C</au><au>SCHMALDIENST, S</au><au>WOLOSZCZUK, W</au><au>FÖRSTER, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tubulointerstitial nephritis and uveitis : an immunological disorder ?</atitle><jtitle>Pediatric nephrology (Berlin, West)</jtitle><addtitle>Pediatr Nephrol</addtitle><date>1995-04-01</date><risdate>1995</risdate><volume>9</volume><issue>2</issue><spage>193</spage><epage>195</epage><pages>193-195</pages><issn>0931-041X</issn><eissn>1432-198X</eissn><coden>PENED3</coden><abstract>A 14-year-old boy with tubulointerstitial nephritis and uveitis (TINU syndrome) is described. 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| fulltext | fulltext |
| identifier | ISSN: 0931-041X |
| ispartof | Pediatric nephrology (Berlin, West), 1995-04, Vol.9 (2), p.193-195 |
| issn | 0931-041X 1432-198X |
| language | eng |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Adolescent Biological and medical sciences Humans Interstitial nephritis Male Medical sciences Nephritis, Interstitial - immunology Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Syndrome Uveitis - immunology |
| title | Tubulointerstitial nephritis and uveitis : an immunological disorder ? |
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