Intricate combinatorial patterns of exon splicing generate multiple Rh-related isoforms in human erythroid cells

The Rhesus (Rh) blood group system shows complex polymorphisms in the human. Some of the heterogeneity may be generated by alternative RNA splicing. For a systematic analysis of Rh-related mRNA isoforms expressed in reticulocytes, we isolated mRNA, which was then reverse transcribed and amplified by...

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Veröffentlicht in:	Human genetics 1995-06, Vol.95 (6), p.657-665
Hauptverfasser:	KAJII, E, UMENISHI, F, OMI, T, IKEMOTO, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing - genetics Amino Acid Sequence Base Sequence Biological and medical sciences Blood Proteins - chemistry Blood Proteins - genetics blood transfusion Classical genetics, quantitative genetics, hybrids Cloning, Molecular DNA, Complementary - genetics erythroid cells Exons - genetics Fundamental and applied biological sciences. Psychology Genetic Variation Genetics of eukaryotes. Biological and molecular evolution Human Humans man Molecular Sequence Data Polymerase Chain Reaction polymorphism Protein Conformation Reticulocytes - physiology Rh system Rh-Hr Blood-Group System - genetics Sequence Analysis, DNA Sequence Homology, Amino Acid splicing
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