L1 and N‐CAM Antibodies Trigger Protein Phosphatase Activity in Growth Cone‐Enriched Membranes

: Triggering of the cell adhesion molecules L1 or N‐CAM in a nerve growth cone membrane fraction from fetal rat brain with purified L1 or N‐CAM or specific antibodies decreases the steady‐state levels of protein tyrosine phosphorylation in the membranes. Here we report that triggering of L1 and N‐CA...

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Veröffentlicht in:	Journal of neurochemistry 1995-07, Vol.65 (1), p.84-95
Hauptverfasser:	Klinz, Stephan G., Schachner, Melitta, Maness, Patricia F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - analysis Animals Antibodies - physiology Axons - metabolism Biological and medical sciences Brain - metabolism Cell adhesion molecule Cell Adhesion Molecules, Neuronal - immunology Cells, Cultured Development. Senescence. Regeneration. Transplantation Enzyme Activation Fundamental and applied biological sciences. Psychology Growth cone membranes Leukocyte L1 Antigen Complex Membrane Proteins - chemistry Membranes - metabolism Molecular Weight Phosphoprotein Phosphatases - antagonists & inhibitors Phosphoprotein Phosphatases - metabolism Protein phosphatase Protein tyrosine kinase Rats Rats, Sprague-Dawley Signal transduction Tubulin - chemistry Tyrosine phosphorylation Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
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