A fraction enriched in dendrodendritic synaptosomes isolated from rat olfactory bulb: morphology and transmitter release
A fraction enriched in dendro-dendritic synaptosomes was isolated from rat olfactory bulb by a rapid method. Synaptosomes preserved their ultrastructure and showed configurational changes in relation to incubation in physiological ion medium as described earlier in the case of cortical synaptosomes....
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| Veröffentlicht in: | Neurochemical research 1986-11, Vol.11 (11), p.1597-1607 |
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| container_issue | 11 |
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| container_title | Neurochemical research |
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| creator | Chiflikian, M D Kálmán, M Galoyan, A A Hajós, F |
| description | A fraction enriched in dendro-dendritic synaptosomes was isolated from rat olfactory bulb by a rapid method. Synaptosomes preserved their ultrastructure and showed configurational changes in relation to incubation in physiological ion medium as described earlier in the case of cortical synaptosomes. Dendro-dendritic synaptosomes were larger and contained more mitochondria than cortical synaptosomes. Doublets of terminals synapsing with each other were frequently seen and each terminal contained synaptic vesicles. Oxygen consumption of dendro-dendritic synaptosomes was decreased by ouabain and increased by 2,4-dinitrophenol. High-potassium medium evoked a considerable release of GABA and dopamine but not of noradrenaline or serotonin in accordance with histochemical published data. |
| doi_str_mv | 10.1007/BF00965778 |
| format | Article |
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High-potassium medium evoked a considerable release of GABA and dopamine but not of noradrenaline or serotonin in accordance with histochemical published data.</description><subject>Animals</subject><subject>Cell Fractionation - methods</subject><subject>Centrifugation, Density Gradient - methods</subject><subject>Dendrites - metabolism</subject><subject>Dendrites - ultrastructure</subject><subject>Dopamine - metabolism</subject><subject>gamma-Aminobutyric Acid - metabolism</subject><subject>Microscopy, Electron</subject><subject>Neurotransmitter Agents - metabolism</subject><subject>Norepinephrine - metabolism</subject><subject>Olfactory Bulb - metabolism</subject><subject>Olfactory Bulb - ultrastructure</subject><subject>Rats</subject><subject>Serotonin - metabolism</subject><subject>Synaptosomes - metabolism</subject><subject>Synaptosomes - ultrastructure</subject><issn>0364-3190</issn><issn>1573-6903</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0D1PwzAUhWELgUopLOxInhiQAv7AccxWKgpIlVhgjmznhholcbAdifx7Aq1guXd59A4HoXNKrikh8uZ-TYjKhZTFAZpTIXmWK8IP0Zzw_DbjVJFjdBLjByETZ3SGZqxQlIhijr6WuA7aJuc7DF1wdgsVdh2uoKuC_70uOYvj2Ok--ehbiNhF3-g0wTr4FgedsG_qKeLDiM3QmDvc-tBvfePfR6y7Cqegu9i6lCDgAA3oCKfoqNZNhLP9X6C39cPr6inbvDw-r5abzFIlU0YNs8IwLa0UjEheiZxaIUFSkUvOjcmZEMoqo40wlnEBlDLCLQirmLYVX6DLXbcP_nOAmMrWRQtNozvwQyzlVBGskBO82kEbfIwB6rIPrtVhLCkpf2Yu_2ee8MW-OpgWqj-635V_A1bGedE</recordid><startdate>198611</startdate><enddate>198611</enddate><creator>Chiflikian, M D</creator><creator>Kálmán, M</creator><creator>Galoyan, A A</creator><creator>Hajós, F</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198611</creationdate><title>A fraction enriched in dendrodendritic synaptosomes isolated from rat olfactory bulb: morphology and transmitter release</title><author>Chiflikian, M D ; Kálmán, M ; Galoyan, A A ; Hajós, F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c197t-1b2c5b2a7c752073d561c57e7156733bb62559c9bab5bc235e11203ce5c92acd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Animals</topic><topic>Cell Fractionation - methods</topic><topic>Centrifugation, Density Gradient - methods</topic><topic>Dendrites - metabolism</topic><topic>Dendrites - ultrastructure</topic><topic>Dopamine - metabolism</topic><topic>gamma-Aminobutyric Acid - metabolism</topic><topic>Microscopy, Electron</topic><topic>Neurotransmitter Agents - metabolism</topic><topic>Norepinephrine - metabolism</topic><topic>Olfactory Bulb - metabolism</topic><topic>Olfactory Bulb - ultrastructure</topic><topic>Rats</topic><topic>Serotonin - metabolism</topic><topic>Synaptosomes - metabolism</topic><topic>Synaptosomes - ultrastructure</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chiflikian, M D</creatorcontrib><creatorcontrib>Kálmán, M</creatorcontrib><creatorcontrib>Galoyan, A A</creatorcontrib><creatorcontrib>Hajós, F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neurochemical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chiflikian, M D</au><au>Kálmán, M</au><au>Galoyan, A A</au><au>Hajós, F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A fraction enriched in dendrodendritic synaptosomes isolated from rat olfactory bulb: morphology and transmitter release</atitle><jtitle>Neurochemical research</jtitle><addtitle>Neurochem Res</addtitle><date>1986-11</date><risdate>1986</risdate><volume>11</volume><issue>11</issue><spage>1597</spage><epage>1607</epage><pages>1597-1607</pages><issn>0364-3190</issn><eissn>1573-6903</eissn><abstract>A fraction enriched in dendro-dendritic synaptosomes was isolated from rat olfactory bulb by a rapid method. 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| fulltext | fulltext |
| identifier | ISSN: 0364-3190 |
| ispartof | Neurochemical research, 1986-11, Vol.11 (11), p.1597-1607 |
| issn | 0364-3190 1573-6903 |
| language | eng |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Animals Cell Fractionation - methods Centrifugation, Density Gradient - methods Dendrites - metabolism Dendrites - ultrastructure Dopamine - metabolism gamma-Aminobutyric Acid - metabolism Microscopy, Electron Neurotransmitter Agents - metabolism Norepinephrine - metabolism Olfactory Bulb - metabolism Olfactory Bulb - ultrastructure Rats Serotonin - metabolism Synaptosomes - metabolism Synaptosomes - ultrastructure |
| title | A fraction enriched in dendrodendritic synaptosomes isolated from rat olfactory bulb: morphology and transmitter release |
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