Potentiation of retinoic acid-induced U-937 differentiation into respiratory burst-competent cells by nitric oxide donors

All- trans retinoic acid (tretinoin) is a known inducer of differentiation of the human monoblastic cell line, U-937. We now report that the ability of retinoic acid (RA) to induce differentiation of U-937 cells into cells possessing respiratory burst activity is enhanced by the known nitric oxide-d...

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