Brucellosis in childhood in the western cape
Human brucellosis, a multisystem disease which may mimic other conditions, has a low incidence in childhood and the diagnosis may easily be missed. Over a 7-month period 9 children with brucellosis presented to the Department of Paediatrics and Child Health, Tygerberg Hospital. Six of the children h...
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| Veröffentlicht in: | South African medical journal 1995-03, Vol.85 (3), p.176-178 |
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| container_title | South African medical journal |
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| creator | HENDRICKS, M. J PEREZ, E. M BURGER, P. J MOUTON, P. A |
| description | Human brucellosis, a multisystem disease which may mimic other conditions, has a low incidence in childhood and the diagnosis may easily be missed. Over a 7-month period 9 children with brucellosis presented to the Department of Paediatrics and Child Health, Tygerberg Hospital. Six of the children had consumed unpasteurized milk. The main presenting symptoms were fever, fatigue, headache, myalgia and haematuria. Clinical signs included lymphadenopathy (3), nasopharyngitis (2), features of lower respiratory tract infection (2), splenomegaly (2) and pyrexia (1). The diagnosis was made on the basis of a positive serological titre (> 1:160) for Brucella abortus. The prozone phenomenon was encountered in 6 cases; however, the Coombs test confirmed the diagnosis in these cases. Children under 7 years were treated with co-trimoxazole and rifampicin and those over 7 years with tetracycline and rifampicin, for at least 6 weeks. No relapses were detected on follow-up. |
| format | Article |
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J ; PEREZ, E. M ; BURGER, P. J ; MOUTON, P. A</creator><creatorcontrib>HENDRICKS, M. J ; PEREZ, E. M ; BURGER, P. J ; MOUTON, P. A</creatorcontrib><description>Human brucellosis, a multisystem disease which may mimic other conditions, has a low incidence in childhood and the diagnosis may easily be missed. Over a 7-month period 9 children with brucellosis presented to the Department of Paediatrics and Child Health, Tygerberg Hospital. Six of the children had consumed unpasteurized milk. The main presenting symptoms were fever, fatigue, headache, myalgia and haematuria. Clinical signs included lymphadenopathy (3), nasopharyngitis (2), features of lower respiratory tract infection (2), splenomegaly (2) and pyrexia (1). The diagnosis was made on the basis of a positive serological titre (> 1:160) for Brucella abortus. The prozone phenomenon was encountered in 6 cases; however, the Coombs test confirmed the diagnosis in these cases. Children under 7 years were treated with co-trimoxazole and rifampicin and those over 7 years with tetracycline and rifampicin, for at least 6 weeks. No relapses were detected on follow-up.</description><identifier>ISSN: 0256-9574</identifier><identifier>PMID: 7777972</identifier><identifier>CODEN: SAMJAF</identifier><language>eng</language><publisher>Pinelands: Medical Association of South Africa</publisher><subject>Adolescent ; Animal bacterial diseases ; Animals ; Bacterial diseases ; Biological and medical sciences ; Brucellosis - diagnosis ; Brucellosis - epidemiology ; Brucellosis - etiology ; Brucellosis - therapy ; Child ; Child, Preschool ; Female ; Humans ; Incidence ; Infant ; Infectious diseases ; Male ; Medical sciences ; Milk - adverse effects ; Rural Population ; South Africa - epidemiology ; Tropical medicine ; Urban Population</subject><ispartof>South African medical journal, 1995-03, Vol.85 (3), p.176-178</ispartof><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3484313$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7777972$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HENDRICKS, M. J</creatorcontrib><creatorcontrib>PEREZ, E. M</creatorcontrib><creatorcontrib>BURGER, P. J</creatorcontrib><creatorcontrib>MOUTON, P. A</creatorcontrib><title>Brucellosis in childhood in the western cape</title><title>South African medical journal</title><addtitle>S Afr Med J</addtitle><description>Human brucellosis, a multisystem disease which may mimic other conditions, has a low incidence in childhood and the diagnosis may easily be missed. Over a 7-month period 9 children with brucellosis presented to the Department of Paediatrics and Child Health, Tygerberg Hospital. Six of the children had consumed unpasteurized milk. The main presenting symptoms were fever, fatigue, headache, myalgia and haematuria. Clinical signs included lymphadenopathy (3), nasopharyngitis (2), features of lower respiratory tract infection (2), splenomegaly (2) and pyrexia (1). The diagnosis was made on the basis of a positive serological titre (> 1:160) for Brucella abortus. The prozone phenomenon was encountered in 6 cases; however, the Coombs test confirmed the diagnosis in these cases. Children under 7 years were treated with co-trimoxazole and rifampicin and those over 7 years with tetracycline and rifampicin, for at least 6 weeks. No relapses were detected on follow-up.</description><subject>Adolescent</subject><subject>Animal bacterial diseases</subject><subject>Animals</subject><subject>Bacterial diseases</subject><subject>Biological and medical sciences</subject><subject>Brucellosis - diagnosis</subject><subject>Brucellosis - epidemiology</subject><subject>Brucellosis - etiology</subject><subject>Brucellosis - therapy</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Humans</subject><subject>Incidence</subject><subject>Infant</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Milk - adverse effects</subject><subject>Rural Population</subject><subject>South Africa - epidemiology</subject><subject>Tropical medicine</subject><subject>Urban Population</subject><issn>0256-9574</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9j01LxDAQhnNQ1nX1Jwg9iCcL-WrSHHXRVVjwoueSJlMaSZuatIj_3iwW5zK8PA_DO2doi2klSlVJfoEuU_rEOVdKbNBG5lGSbtH9Y1wMeB-SS4UbC9M7b_sQ7CnMPRTfkGaIGegJrtB5p32C63Xv0Mfz0_v-pTy-HV73D8dyoqyaSytlTYxQuMWqwwRrDYpzEDm0trVYSA6KUkUlJpSamkrO6o5hXBEQIGq2Q3d_d6cYvpZcoBlcOrXUI4QlNVIyygghWbxZxaUdwDZTdIOOP836Xua3K9fJaN9FPRqX_jXGa84IY79hEFUI</recordid><startdate>19950301</startdate><enddate>19950301</enddate><creator>HENDRICKS, M. 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J</creatorcontrib><creatorcontrib>PEREZ, E. M</creatorcontrib><creatorcontrib>BURGER, P. J</creatorcontrib><creatorcontrib>MOUTON, P. A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>South African medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HENDRICKS, M. J</au><au>PEREZ, E. M</au><au>BURGER, P. J</au><au>MOUTON, P. A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Brucellosis in childhood in the western cape</atitle><jtitle>South African medical journal</jtitle><addtitle>S Afr Med J</addtitle><date>1995-03-01</date><risdate>1995</risdate><volume>85</volume><issue>3</issue><spage>176</spage><epage>178</epage><pages>176-178</pages><issn>0256-9574</issn><coden>SAMJAF</coden><abstract>Human brucellosis, a multisystem disease which may mimic other conditions, has a low incidence in childhood and the diagnosis may easily be missed. Over a 7-month period 9 children with brucellosis presented to the Department of Paediatrics and Child Health, Tygerberg Hospital. Six of the children had consumed unpasteurized milk. The main presenting symptoms were fever, fatigue, headache, myalgia and haematuria. Clinical signs included lymphadenopathy (3), nasopharyngitis (2), features of lower respiratory tract infection (2), splenomegaly (2) and pyrexia (1). The diagnosis was made on the basis of a positive serological titre (> 1:160) for Brucella abortus. The prozone phenomenon was encountered in 6 cases; however, the Coombs test confirmed the diagnosis in these cases. Children under 7 years were treated with co-trimoxazole and rifampicin and those over 7 years with tetracycline and rifampicin, for at least 6 weeks. No relapses were detected on follow-up.</abstract><cop>Pinelands</cop><pub>Medical Association of South Africa</pub><pmid>7777972</pmid><tpages>3</tpages></addata></record> |
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| ispartof | South African medical journal, 1995-03, Vol.85 (3), p.176-178 |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Adolescent Animal bacterial diseases Animals Bacterial diseases Biological and medical sciences Brucellosis - diagnosis Brucellosis - epidemiology Brucellosis - etiology Brucellosis - therapy Child Child, Preschool Female Humans Incidence Infant Infectious diseases Male Medical sciences Milk - adverse effects Rural Population South Africa - epidemiology Tropical medicine Urban Population |
| title | Brucellosis in childhood in the western cape |
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