Complement—immunoglobulin interactions

Normal circulating immunoglobulin may control complement binding to targets and thereby the manifestations of autoimmune disease. Molecular analysis of IgG and IgM mutants suggests that C1q binding by IgG utilizes a core Glu-X-Lys-X-Lys motif (where X is any amino acid). Additional amino acids, part...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Current opinion in immunology 1995-02, Vol.7 (1), p.41-47
Hauptverfasser:	Miletic, Vojislav D, Frank, Michael M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Complement System Proteins - immunology Humans Immunoglobulins - immunology
Online-Zugang:	Volltext
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