Oligonucleotide synthesis on a cellulose acetate functionalized with a spacer

4-(2-Hydroxyethylsulfonyl)dihydrocinnamate derivative of cellulose acetate (D.S. 1.77) was used for polymer support synthesis of oligonucleotides bearing a phosphodiester function at the 3'-terminal position, taking into consideration that the cellulose derivative is readily soluble in pyridine...

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Veröffentlicht in:	Nucleic acids symposium series (1979) 1986 (17), p.89-92
Hauptverfasser:	Kamaike, K, Yamakage, S, Hasegawa, Y, Ishido, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellulose - analogs & derivatives Indicators and Reagents Oligonucleotides - chemical synthesis Solubility
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creator	Kamaike, K Yamakage, S Hasegawa, Y Ishido, Y
description	4-(2-Hydroxyethylsulfonyl)dihydrocinnamate derivative of cellulose acetate (D.S. 1.77) was used for polymer support synthesis of oligonucleotides bearing a phosphodiester function at the 3'-terminal position, taking into consideration that the cellulose derivative is readily soluble in pyridine, but slightly soluble in a solvent such as ethanol.
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language	eng
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source	MEDLINE; EZB Electronic Journals Library
subjects	Cellulose - analogs & derivatives Indicators and Reagents Oligonucleotides - chemical synthesis Solubility
title	Oligonucleotide synthesis on a cellulose acetate functionalized with a spacer
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