No role of interleukin‐4 in CD23/IgE‐mediated enhancement of the murine antibody response in vivo

Antigen‐specific IgE up‐regulates the specific IgM, IgG1, IgG2a and IgE response in vivo when given to mice together with antigen. The enhancement is mediated by the low‐affinity receptor for IgE, FcϵRII or CD23, as demonstrated both in CD23‐deficient mice and by blocking CD23 with anti‐CD23 monoclo...

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Veröffentlicht in:	European journal of immunology 1995-05, Vol.25 (5), p.1469-1472
Hauptverfasser:	Hjulström, Susanna, Landin, Andreas, Jansson, Liselotte, Holmdahl, Rikard, Heyman, Birgitta
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibody Formation Antibody Specificity B-Lymphocyte Subsets - immunology Base Sequence CD23 Crosses, Genetic Female Gene Expression Regulation IgE Immune regulation Immunoglobulin E - immunology Interleukin-4 - deficiency Interleukin-4 - genetics Interleukin-4 - physiology Interleukin‐4 Macromolecular Substances Male Mice Mice, Knockout Molecular Sequence Data Polymerase Chain Reaction Receptors, IgE - immunology Spleen - pathology
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