Protection of Mice from Group A Streptococcal Skin Infection by Interleukin-12

It has been shown that interleukin (IL)-12 induces cell-mediated immunity and provides significant protection against intracellular organisms. The ability of this cytokine to enhance immunity in a mouse model of group A streptococcal skin infection was studied. Outbred CD1 mice were injected for 3 c...

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Veröffentlicht in:	The Journal of infectious diseases 1995-06, Vol.171 (6), p.1643-1645
Hauptverfasser:	Metzger, Dennis W., Raeder, Roberta, Van Cleave, Victor H., Boyle, Michael D. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria Biological and medical sciences Concise Communications Cytokines Drug Administration Schedule Immunity Immunomodulators Infections Interleukin-12 - administration & dosage Macrophages Medical sciences Mice Natural killer cells Pharmacology. Drug treatments Protective effects Skin Skin Diseases - drug therapy Skin Diseases - prevention & control Streptococcal Infections - drug therapy Streptococcal Infections - prevention & control Streptococcus pyogenes Survival Analysis T lymphocytes
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