Platelet cytosolic Ca2+ and membrane dynamics in patients with primary hypercholesterolemia : effects of pravastatin

This study was designed to evaluate the relationships between platelet cytosolic Ca2+ concentration ([Ca2+]i) and plasma lipids in patients with primary hypercholesterolemia. In a double-blind, placebo-controlled trial, we determined platelet [Ca2+]i in the presence and virtual absence of extracellu...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 1995-06, Vol.15 (6), p.759-764
Hauptverfasser:	KIM-HANH LE QUAN SANG, LEVENSON, J, MEGNIEN, J.-L, SIMON, A, DEVYNCK, M.-A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apolipoproteins B - blood Biological and medical sciences Blood Platelets - metabolism Blood Platelets - ultrastructure Calcium - blood Cell Membrane - physiology Cholesterol, HDL - blood Cholesterol, LDL - blood Cytosol - metabolism Double-Blind Method General and cellular metabolism. Vitamins Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Hyperlipoproteinemia Type II - blood Hyperlipoproteinemia Type II - drug therapy Male Medical sciences Membrane Fluidity Middle Aged Pharmacology. Drug treatments Placebos Pravastatin - therapeutic use Triglycerides - blood Viscosity
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