The Long‐Term Regulation of Skeletal Muscle Pyruvate Dehydrogenase Kinase by Dietary Lipid is Dependent on Fatty Acid Composition

The provision of a diet high in saturated and monounsaturated fat for 28 days evoked a significant (1.9‐fold) increase in pyruvate‐dehydrogenase kinase activity measured in isolated mitochondria from representative slow‐twitch (oxidative) skeletal muscles (pooled soleus and adductor longus muscles)...

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Veröffentlicht in:	European journal of biochemistry 1995-05, Vol.229 (3), p.741-748
Hauptverfasser:	Fryer, Lee G. D., Orfali, Karen A., Holness, Mark J., Saggerson, E. David, Sugden, Mary C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bucladesine - administration & dosage Caprylates - administration & dosage Cells, Cultured Dietary Fats - administration & dosage Fatty Acids - administration & dosage Fatty Acids - chemistry Fatty Acids, Omega-3 - administration & dosage Female high‐fat diet insulin Insulin - pharmacology long‐chain ω–3 fatty acids Membrane Lipids - chemistry Mitochondria, Heart - enzymology Mitochondria, Muscle - enzymology muscle Muscle, Skeletal - enzymology Myocardium - cytology Myocardium - enzymology Protein Kinases - metabolism Protein-Serine-Threonine Kinases Pyruvate‐dehydrogenase kinase Rats Rats, Wistar
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