Cholinergic but not monoaminergic denervation increases nerve growth factor content in the adult rat hippocampus and cerebral cortex

We have investigated whether degeneration of basal forebrain cholinergic neurons is a potential trigger for increased NGF production in the adult rat brain. Electrolytic lesions of cholinergic neurons in the septum-diagonal band and in the nucleus basalis of Meynert induced a transient increase in N...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology 1986-12, Vol.334 (4), p.346-351
Hauptverfasser:	WESKAMP, G, LOREZ, H. P, KELLER, H. H, OTTEN, U
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basal Ganglia - physiology Biogenic Amines - physiology Biological and medical sciences Brain - physiology Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Cerebral Cortex - metabolism Denervation Fundamental and applied biological sciences. Psychology Hippocampus - metabolism Male Medial Forebrain Bundle - physiology Nerve Growth Factors - metabolism Rats Rats, Inbred Strains Receptors, Cholinergic - physiology Vertebrates: nervous system and sense organs
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