Mechanisms of use of extracellular glutathione by lung epithelial cells and pulmonary artery endothelial cells

Cells in most culture media use cystine as the primary source of the cysteine precursor needed for glutathione (GSH) synthesis. As a result, GSH levels in many cultured cells may be limited by the rate of uptake of cystine into cells. We have shown that incubation with extracellular GSH can result i...

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Veröffentlicht in:American journal of respiratory cell and molecular biology 1995-06, Vol.12 (6), p.662-668
Hauptverfasser: Deneke, SM, Susanto, I, Vogel, KA, Williams, CE, Lawrence, RA
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Sprache:eng
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