Umbilical arteries of babies born to cigarette smokers generate less prostacyclin and contain less arginine and citrulline compared with those of babies born to control subjects

OBJECTIVE: The hyposthesis of this study was that umbilical arteries of babies born to smoking mothers produce less nitric oxide and prostacyclin than do those of nonsmoking mothers. STUDY DESIGN: l-Arginine, l-citrulline, l-cysteine, and prostacyclin were measured in the umbilical arteries of 11 ba...

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