The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

DENDRITIC cells and thymic epithelial cells perform important immunoregulatory functions by presenting antigens in the form of peptides bound to cell-surface major histocompatibility complex (MHC) molecules to T cells 1–3 . Whereas B cells are known to present specific antigens efficiently through t...

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Veröffentlicht in:	Nature (London) 1995-05, Vol.375 (6527), p.151-155
Hauptverfasser:	Jiang, Wanping, Swiggard, William J., Heufler, Christine, Peng, Michael, Mirza, Asra, Steinman, Ralph M., Nussenzweig, Michel C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies Antigen Presentation - physiology Antigen-antibody reactions, antigen-antibody complexes, antibody-complement and others. Study of affinity. Antigen presentation Antigens Antigens, CD Biological and medical sciences Carbohydrates Cells, Cultured Cellular biology Dendritic Cells - physiology Endocytosis Epithelial Cells Epithelium - physiology Fundamental and applied biological sciences. Psychology Fundamental immunology Humanities and Social Sciences Humans Immunity (Disease) Lectins, C-Type letter Mannose-Binding Lectins Mice Mice, Inbred BALB C Minor Histocompatibility Antigens Molecular immunology Molecular Sequence Data multidisciplinary Peptides Proteins Receptors, Cell Surface - chemistry Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism Science Science (multidisciplinary) Sequence Homology, Amino Acid Thymus Gland - cytology
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