Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants

THE identity and patterning of ventral cell types in the vertebrate central nervous system depends on cell interactions 1 . For example, induction of a specialized population of ventral midline cells, the floor plate, appears to require contact-mediated signalling by the underlying notochord, wherea...

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Veröffentlicht in:	Nature (London) 1995-05, Vol.375 (6529), p.322-325
Hauptverfasser:	Marti, Elisa, Bumcrot, David A, Takada, Ritsuko, McMahon, Andrew P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - immunology Binding Sites Biological and medical sciences Cellular biology Central nervous system Central Nervous System - cytology Central Nervous System - embryology Chick Embryo Development. Senescence. Regeneration. Transplantation Embryonic Induction Fundamental and applied biological sciences. Psychology Hedgehog Proteins Humanities and Social Sciences letter Mice Motor Neurons - cytology multidisciplinary Nerve Growth Factors - genetics Nerve Growth Factors - metabolism Nerve Growth Factors - physiology Nervous system Neurons Notochord - embryology Peptides Protein Processing, Post-Translational Proteins - genetics Proteins - metabolism Proteins - physiology Recombinant Proteins Science Science (multidisciplinary) Tissue Transplantation Trans-Activators Vertebrates Vertebrates: nervous system and sense organs
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