CLINICAL EVALUATION OF ASTROMICIN ADMINISTERED BY INTRAVENOUS DRIP INFUSION: REPORT III. BACTERIAL INFECTIONS IN A FIELD OF UROLOGY
Intravenous drip infusion of a new aminoglycoside agent, astromicin (ASTM), was used for various urological infections, and its clinical efficacy and safety were studied. Each of almost all the patients tested was given 200mg of ASTM twice a day by intravenous drip infusion. Among 114 cases with com...
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| Veröffentlicht in: | Japanese journal of antibiotics 1986/11/25, Vol.39(11), pp.2945-2958 |
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| creator | KAWAMURA, NOBUO OKADA, KEISHI TANAKA, NORIAKI KUMAMOTO, YOSHIAKI KISHI, HIROICHI NIIJIMA, TADAO GOTO, HIROICHI MACHIDA, TOYOHEI SUZUKI, KEIZO NAIDE, YORIO UEDA, KOHSUKE OHTAGURO, KAZUO SAITO, AKIHIRO BAN, YOSHIHITO OKADA, KENICHIRO YOSHIDA, OSAMU KAWABATA, GAKU KAMIDONO, SADAO KUMON, HIROMI OHMORI, HIROYUKI MATSUMOTO, TETSURO KUMAZAWA, JOICHI UEDA, SHOGO ETOH, KOSAKU KITAYAMA, TOSHIO SAITO, YUTAKA GOTO, TOSHIHIRO OHI, YOSHITADA |
| description | Intravenous drip infusion of a new aminoglycoside agent, astromicin (ASTM), was used for various urological infections, and its clinical efficacy and safety were studied. Each of almost all the patients tested was given 200mg of ASTM twice a day by intravenous drip infusion. Among 114 cases with complicated urinary tract infections (UTI) evaluated according to the criteria for evaluation of drug efficacy in UTI, clinical response was excellent in 16, moderate in 54 and poor in 44. The efficacy rate was 61.4%. Among 137 cases who were evaluated for side effects, headache was observed in 1 case (0.7%), which recovered spontaneously the day after the withdrawal of the drug. Slight elevation in S-GOT, S-GPT, Al-P and others was observed in 12 cases (8.8%) as abnormal labo-ratory test values. |
| doi_str_mv | 10.11553/antibiotics1968b.39.2945 |
| format | Article |
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Each of almost all the patients tested was given 200mg of ASTM twice a day by intravenous drip infusion. Among 114 cases with complicated urinary tract infections (UTI) evaluated according to the criteria for evaluation of drug efficacy in UTI, clinical response was excellent in 16, moderate in 54 and poor in 44. The efficacy rate was 61.4%. Among 137 cases who were evaluated for side effects, headache was observed in 1 case (0.7%), which recovered spontaneously the day after the withdrawal of the drug. 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BACTERIAL INFECTIONS IN A FIELD OF UROLOGY</title><title>Japanese journal of antibiotics</title><addtitle>Jpn. J. Antibiotics</addtitle><description>Intravenous drip infusion of a new aminoglycoside agent, astromicin (ASTM), was used for various urological infections, and its clinical efficacy and safety were studied. Each of almost all the patients tested was given 200mg of ASTM twice a day by intravenous drip infusion. Among 114 cases with complicated urinary tract infections (UTI) evaluated according to the criteria for evaluation of drug efficacy in UTI, clinical response was excellent in 16, moderate in 54 and poor in 44. The efficacy rate was 61.4%. Among 137 cases who were evaluated for side effects, headache was observed in 1 case (0.7%), which recovered spontaneously the day after the withdrawal of the drug. Slight elevation in S-GOT, S-GPT, Al-P and others was observed in 12 cases (8.8%) as abnormal labo-ratory test values.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aminoglycosides - administration & dosage</subject><subject>Aminoglycosides - pharmacology</subject><subject>Aminoglycosides - therapeutic use</subject><subject>Anti-Bacterial Agents</subject><subject>Bacterial Infections - drug therapy</subject><subject>Drug Resistance, Microbial</subject><subject>Escherichia coli - drug effects</subject><subject>Female</subject><subject>Humans</subject><subject>Infusions, Intravenous</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pseudomonas aeruginosa - drug effects</subject><subject>Serratia - drug effects</subject><subject>Urinary Tract Infections - drug therapy</subject><issn>0368-2781</issn><issn>2186-5477</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkEtPg1AQhW-Mpja1P8EEN-6o99H7WiKlSqRgeDRxRS7ci2LoQ6AL_700bbpwM5PM-eZM5gDwgOAMIUrJk9r2dVHv-rrskGSimBE5w3JOr8AYI8FsOuf8GowhYcLGXKBbMO26uoAEcYEHixEYEQSxgHwM3tzAD33XCSxv7QSZk_pRaEVLy0nSOFr5rh9azmI1IEnqxd7Cev6w_DCNnbUXRlliLWL_fRgss2TYuwM3lWo6Mz33CciWXuq-2kH0cjxhfyMJe7vSVFDEygpqrYigkKiCIkOpQpqICmKJScEgg6WGVBJZCm4w1iWsBNPEVGQCHk---3b3czBdn2_qrjRNo7Zmd-hyzjGXkMkBvD-Dh2JjdL5v641qf_Pz94MenPTvrlef5qKrdsi2Mfn_oHMic4SO9Rj3BSu_VJubLfkD3tt1Sw</recordid><startdate>198611</startdate><enddate>198611</enddate><creator>KAWAMURA, NOBUO</creator><creator>OKADA, KEISHI</creator><creator>TANAKA, NORIAKI</creator><creator>KUMAMOTO, YOSHIAKI</creator><creator>KISHI, HIROICHI</creator><creator>NIIJIMA, TADAO</creator><creator>GOTO, HIROICHI</creator><creator>MACHIDA, TOYOHEI</creator><creator>SUZUKI, KEIZO</creator><creator>NAIDE, YORIO</creator><creator>UEDA, KOHSUKE</creator><creator>OHTAGURO, KAZUO</creator><creator>SAITO, AKIHIRO</creator><creator>BAN, YOSHIHITO</creator><creator>OKADA, KENICHIRO</creator><creator>YOSHIDA, OSAMU</creator><creator>KAWABATA, GAKU</creator><creator>KAMIDONO, SADAO</creator><creator>KUMON, HIROMI</creator><creator>OHMORI, HIROYUKI</creator><creator>MATSUMOTO, TETSURO</creator><creator>KUMAZAWA, JOICHI</creator><creator>UEDA, SHOGO</creator><creator>ETOH, KOSAKU</creator><creator>KITAYAMA, TOSHIO</creator><creator>SAITO, YUTAKA</creator><creator>GOTO, TOSHIHIRO</creator><creator>OHI, YOSHITADA</creator><general>Japan Antibiotics Research Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198611</creationdate><title>CLINICAL EVALUATION OF ASTROMICIN ADMINISTERED BY INTRAVENOUS DRIP INFUSION</title><author>KAWAMURA, NOBUO ; 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BACTERIAL INFECTIONS IN A FIELD OF UROLOGY</atitle><jtitle>Japanese journal of antibiotics</jtitle><addtitle>Jpn. J. Antibiotics</addtitle><date>1986-11</date><risdate>1986</risdate><volume>39</volume><issue>11</issue><spage>2945</spage><epage>2958</epage><pages>2945-2958</pages><issn>0368-2781</issn><eissn>2186-5477</eissn><abstract>Intravenous drip infusion of a new aminoglycoside agent, astromicin (ASTM), was used for various urological infections, and its clinical efficacy and safety were studied. Each of almost all the patients tested was given 200mg of ASTM twice a day by intravenous drip infusion. Among 114 cases with complicated urinary tract infections (UTI) evaluated according to the criteria for evaluation of drug efficacy in UTI, clinical response was excellent in 16, moderate in 54 and poor in 44. The efficacy rate was 61.4%. Among 137 cases who were evaluated for side effects, headache was observed in 1 case (0.7%), which recovered spontaneously the day after the withdrawal of the drug. Slight elevation in S-GOT, S-GPT, Al-P and others was observed in 12 cases (8.8%) as abnormal labo-ratory test values.</abstract><cop>Japan</cop><pub>Japan Antibiotics Research Association</pub><pmid>3102807</pmid><doi>10.11553/antibiotics1968b.39.2945</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0368-2781 |
| ispartof | The Japanese Journal of Antibiotics, 1986/11/25, Vol.39(11), pp.2945-2958 |
| issn | 0368-2781 2186-5477 |
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| subjects | Adolescent Adult Aged Aminoglycosides - administration & dosage Aminoglycosides - pharmacology Aminoglycosides - therapeutic use Anti-Bacterial Agents Bacterial Infections - drug therapy Drug Resistance, Microbial Escherichia coli - drug effects Female Humans Infusions, Intravenous Male Middle Aged Pseudomonas aeruginosa - drug effects Serratia - drug effects Urinary Tract Infections - drug therapy |
| title | CLINICAL EVALUATION OF ASTROMICIN ADMINISTERED BY INTRAVENOUS DRIP INFUSION: REPORT III. BACTERIAL INFECTIONS IN A FIELD OF UROLOGY |
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