Synovial Fluid L-Lactic Acid in Acute Arthritis of the Adult Knee Joint

Determination of synovial fluid (SF) lactic acid has been suggested to be an unspecific indicator of SF leukocytosis, and it is not recommended for differential diagnosis of bacterial arthritis. We analyzed the L-lactic acid content by enzymatic UV-method in 65 SF samples obtained from adult patient...

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Veröffentlicht in:Scandinavian journal of rheumatology 1995, Vol.24 (2), p.98-101
Hauptverfasser: Kortekangas, P., Peltola, O., Toivanen, A., Aro, H. T.
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container_end_page 101
container_issue 2
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container_title Scandinavian journal of rheumatology
container_volume 24
creator Kortekangas, P.
Peltola, O.
Toivanen, A.
Aro, H. T.
description Determination of synovial fluid (SF) lactic acid has been suggested to be an unspecific indicator of SF leukocytosis, and it is not recommended for differential diagnosis of bacterial arthritis. We analyzed the L-lactic acid content by enzymatic UV-method in 65 SF samples obtained from adult patients with acute knee arthritides. The concentration of L-lactic acid was not high in any SFs with intensive leukocytosis. The mean concentration of L-lactic acid was 13.5 mmol/l (95% confidence intervals 9.4;17,6 mmol/1) in the synovial-fluid samples from culture-positive arthritis and 5.5 mmol/l (4.9;6.2 mmol/l) in the synovial-fluid samples from culture-negative arthritis. Determination of SF L-lactic acid is an important part of the diagnostic setup for acute arthritis. Values >9 mmol/l strongly support occurrence of bacterial arthritis and indicates an immediate onset of the treatment.
doi_str_mv 10.3109/03009749509099292
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T.</creatorcontrib><title>Synovial Fluid L-Lactic Acid in Acute Arthritis of the Adult Knee Joint</title><title>Scandinavian journal of rheumatology</title><addtitle>Scand J Rheumatol</addtitle><description>Determination of synovial fluid (SF) lactic acid has been suggested to be an unspecific indicator of SF leukocytosis, and it is not recommended for differential diagnosis of bacterial arthritis. We analyzed the L-lactic acid content by enzymatic UV-method in 65 SF samples obtained from adult patients with acute knee arthritides. The concentration of L-lactic acid was not high in any SFs with intensive leukocytosis. The mean concentration of L-lactic acid was 13.5 mmol/l (95% confidence intervals 9.4;17,6 mmol/1) in the synovial-fluid samples from culture-positive arthritis and 5.5 mmol/l (4.9;6.2 mmol/l) in the synovial-fluid samples from culture-negative arthritis. Determination of SF L-lactic acid is an important part of the diagnostic setup for acute arthritis. 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source MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete
subjects Acute Disease
Adolescent
Adult
Aged
Arthritis - metabolism
Arthritis, Infectious - metabolism
Arthritis, Infectious - microbiology
bacterial arthritis
Bacterial arthritis and osteitis
Bacterial diseases
Bacterial Infections - metabolism
Bacterial Infections - microbiology
Biological and medical sciences
Female
Human bacterial diseases
Humans
Infectious diseases
joint fluid
Knee Joint - metabolism
Lactates - metabolism
Lactic Acid
Male
Medical sciences
Middle Aged
Osmolar Concentration
Prospective Studies
septic arthritis
Synovial Fluid - metabolism
Synovial Fluid - microbiology
title Synovial Fluid L-Lactic Acid in Acute Arthritis of the Adult Knee Joint
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