Synovial Fluid L-Lactic Acid in Acute Arthritis of the Adult Knee Joint
Determination of synovial fluid (SF) lactic acid has been suggested to be an unspecific indicator of SF leukocytosis, and it is not recommended for differential diagnosis of bacterial arthritis. We analyzed the L-lactic acid content by enzymatic UV-method in 65 SF samples obtained from adult patient...
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Veröffentlicht in: | Scandinavian journal of rheumatology 1995, Vol.24 (2), p.98-101 |
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description | Determination of synovial fluid (SF) lactic acid has been suggested to be an unspecific indicator of SF leukocytosis, and it is not recommended for differential diagnosis of bacterial arthritis. We analyzed the L-lactic acid content by enzymatic UV-method in 65 SF samples obtained from adult patients with acute knee arthritides. The concentration of L-lactic acid was not high in any SFs with intensive leukocytosis. The mean concentration of L-lactic acid was 13.5 mmol/l (95% confidence intervals 9.4;17,6 mmol/1) in the synovial-fluid samples from culture-positive arthritis and 5.5 mmol/l (4.9;6.2 mmol/l) in the synovial-fluid samples from culture-negative arthritis. Determination of SF L-lactic acid is an important part of the diagnostic setup for acute arthritis. Values >9 mmol/l strongly support occurrence of bacterial arthritis and indicates an immediate onset of the treatment. |
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T.</creatorcontrib><title>Synovial Fluid L-Lactic Acid in Acute Arthritis of the Adult Knee Joint</title><title>Scandinavian journal of rheumatology</title><addtitle>Scand J Rheumatol</addtitle><description>Determination of synovial fluid (SF) lactic acid has been suggested to be an unspecific indicator of SF leukocytosis, and it is not recommended for differential diagnosis of bacterial arthritis. We analyzed the L-lactic acid content by enzymatic UV-method in 65 SF samples obtained from adult patients with acute knee arthritides. The concentration of L-lactic acid was not high in any SFs with intensive leukocytosis. The mean concentration of L-lactic acid was 13.5 mmol/l (95% confidence intervals 9.4;17,6 mmol/1) in the synovial-fluid samples from culture-positive arthritis and 5.5 mmol/l (4.9;6.2 mmol/l) in the synovial-fluid samples from culture-negative arthritis. Determination of SF L-lactic acid is an important part of the diagnostic setup for acute arthritis. Values >9 mmol/l strongly support occurrence of bacterial arthritis and indicates an immediate onset of the treatment.</description><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Arthritis - metabolism</subject><subject>Arthritis, Infectious - metabolism</subject><subject>Arthritis, Infectious - microbiology</subject><subject>bacterial arthritis</subject><subject>Bacterial arthritis and osteitis</subject><subject>Bacterial diseases</subject><subject>Bacterial Infections - metabolism</subject><subject>Bacterial Infections - microbiology</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>joint fluid</subject><subject>Knee Joint - metabolism</subject><subject>Lactates - metabolism</subject><subject>Lactic Acid</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Osmolar Concentration</subject><subject>Prospective Studies</subject><subject>septic arthritis</subject><subject>Synovial Fluid - metabolism</subject><subject>Synovial Fluid - microbiology</subject><issn>0300-9742</issn><issn>1502-7732</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtrGzEUhUVpSZ3HD-giMIvS3TRXjxlJtBtj8mhqyCLJerjRaLCCPEolTYL_fWXsBEohG12k853D1SHkC4XvnII-Aw6gpdANaNCaafaBzGgDrJaSs49kttXrArDP5DClRwAQWuoDciClkLShM3J5uxnDs0NfXfjJ9dWyXqLJzlRzU25uLHPKtprHvIouu1SFocqr8tBPPle_R2ur6-DGfEw-DeiTPdnPI3J_cX63uKqXN5e_FvNlbQSHXBvoexwM0vZBloMJZTX2CIANbxultETVtCCVVYIyFCCYbTVyGEC1ZmD8iHzb5T7F8GeyKXdrl4z1HkcbptRJySQIrgpId6CJIaVoh-4pujXGTUeh25bX_Vde8Zzuw6eHte3fHPu2iv51r2My6IeIo3HpDeNCC6q2MT93mBuHENf4EqLvu4wbH-Krh7-3xY9_7CuLPq8MRts9himOpd53_vAX5C2ZWg</recordid><startdate>1995</startdate><enddate>1995</enddate><creator>Kortekangas, P.</creator><creator>Peltola, O.</creator><creator>Toivanen, A.</creator><creator>Aro, H. T.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1995</creationdate><title>Synovial Fluid L-Lactic Acid in Acute Arthritis of the Adult Knee Joint</title><author>Kortekangas, P. ; Peltola, O. ; Toivanen, A. ; Aro, H. T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-c0ddafca16b7a16248e9ada00a53658897a856078e8412a4042e69a30f086cf23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Acute Disease</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Arthritis - metabolism</topic><topic>Arthritis, Infectious - metabolism</topic><topic>Arthritis, Infectious - microbiology</topic><topic>bacterial arthritis</topic><topic>Bacterial arthritis and osteitis</topic><topic>Bacterial diseases</topic><topic>Bacterial Infections - metabolism</topic><topic>Bacterial Infections - microbiology</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>joint fluid</topic><topic>Knee Joint - metabolism</topic><topic>Lactates - metabolism</topic><topic>Lactic Acid</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Osmolar Concentration</topic><topic>Prospective Studies</topic><topic>septic arthritis</topic><topic>Synovial Fluid - metabolism</topic><topic>Synovial Fluid - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kortekangas, P.</creatorcontrib><creatorcontrib>Peltola, O.</creatorcontrib><creatorcontrib>Toivanen, A.</creatorcontrib><creatorcontrib>Aro, H. 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T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synovial Fluid L-Lactic Acid in Acute Arthritis of the Adult Knee Joint</atitle><jtitle>Scandinavian journal of rheumatology</jtitle><addtitle>Scand J Rheumatol</addtitle><date>1995</date><risdate>1995</risdate><volume>24</volume><issue>2</issue><spage>98</spage><epage>101</epage><pages>98-101</pages><issn>0300-9742</issn><eissn>1502-7732</eissn><coden>SJRHAT</coden><abstract>Determination of synovial fluid (SF) lactic acid has been suggested to be an unspecific indicator of SF leukocytosis, and it is not recommended for differential diagnosis of bacterial arthritis. We analyzed the L-lactic acid content by enzymatic UV-method in 65 SF samples obtained from adult patients with acute knee arthritides. The concentration of L-lactic acid was not high in any SFs with intensive leukocytosis. The mean concentration of L-lactic acid was 13.5 mmol/l (95% confidence intervals 9.4;17,6 mmol/1) in the synovial-fluid samples from culture-positive arthritis and 5.5 mmol/l (4.9;6.2 mmol/l) in the synovial-fluid samples from culture-negative arthritis. Determination of SF L-lactic acid is an important part of the diagnostic setup for acute arthritis. Values >9 mmol/l strongly support occurrence of bacterial arthritis and indicates an immediate onset of the treatment.</abstract><cop>Colchester</cop><pub>Informa UK Ltd</pub><pmid>7747151</pmid><doi>10.3109/03009749509099292</doi><tpages>4</tpages></addata></record> |
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subjects | Acute Disease Adolescent Adult Aged Arthritis - metabolism Arthritis, Infectious - metabolism Arthritis, Infectious - microbiology bacterial arthritis Bacterial arthritis and osteitis Bacterial diseases Bacterial Infections - metabolism Bacterial Infections - microbiology Biological and medical sciences Female Human bacterial diseases Humans Infectious diseases joint fluid Knee Joint - metabolism Lactates - metabolism Lactic Acid Male Medical sciences Middle Aged Osmolar Concentration Prospective Studies septic arthritis Synovial Fluid - metabolism Synovial Fluid - microbiology |
title | Synovial Fluid L-Lactic Acid in Acute Arthritis of the Adult Knee Joint |
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