Mutations in Paralogous Hox Genes Result in Overlapping Homeotic Transformations of the Axial Skeleton: Evidence for Unique and Redundant Function

Hoxd-4 (previously known as Hox-4.2 and - 5.1) is a mouse homeobox-containing gene homologous to the Drosophila homeotic gene Deformed. During embryogenesis, Hoxd-4 is expressed in the presumptive hindbrain and spinal cord, prevertebrae, and other tissues. In the adult, Hoxd-4 transcripts are expres...

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