N-methyl-D-aspartate receptors modulate neurotransmitter release and peristalsis in the guinea pig isolated colon

To assess the role of NMDA receptors in modulating neurotransmitter release in the myenteric plexus, we studied the effects of L-glutamic acid and NMDA on endogenous acetylcholine and noradrenaline overflow (assayed by HPLC) from the guinea pig isolated distal colon. L-Glutamic acid and NMDA enhance...

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Veröffentlicht in:	Neuroscience letters 1995-01, Vol.183 (1-2), p.139-142
Hauptverfasser:	COSENTINO, M, DE PONTI, F, MARINO, F, GIARONI, C, LEONI, O, LECCHINI, S, FRIGO, G
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Amino-5-phosphonovalerate - pharmacology Acetylcholine - metabolism Animals Biological and medical sciences Colon - physiology Fundamental and applied biological sciences. Psychology Glutamic Acid - pharmacology Guinea Pigs Intestine. Mesentery Magnesium - pharmacology N-Methylaspartate - pharmacology Neurotransmitter Agents - metabolism Norepinephrine - metabolism Peristalsis - physiology Receptors, N-Methyl-D-Aspartate - physiology Vertebrates: digestive system
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