Detection of neuroblastoma cells in bone marrow and peripheral blood at diagnosis by the reverse transcriptase‐polymerase chain reaction for tyrosine hydroxylase mRNA

Background. Bone marrow metastasis often occurs in patients with neuroblastoma; therefore, a sensitive assay to detect occult neuroblastoma cells in bone marrow (BM) and peripheral blood (PB) is needed. The feasibility and clinical value of using the reverse transcriptase‐ (RT) polymerase chain reac...

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