Structure and Rotational Dynamics of Fluorescently Labeled Insulin in Aqueous Solution and at the Amphiphile-Water Interface of Reversed Micelles

Insulin is a proteohormone with amphipathic three-dimensional structure and the ligand of a receptor, which itself spans the plasma membrane of glucose-metabolizing cells. In this study, the possible impact of amphiphiles on structural and dynamic properties of the hormone was investigated in revers...

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Veröffentlicht in:	Biochemistry (Easton) 1995-05, Vol.34 (18), p.6130-6141
Hauptverfasser:	Lenz, Volker J, Federwisch, Matthias, Gattner, Hans-Gregor, Brandenburg, Dietrich, Hoecker, Hartwig, Hassiepen, Ulrich, Wollmer, Axel
Format:	Artikel
Sprache:	eng
Schlagworte:	Fluorescent Dyes Insulin - chemistry Micelles Protein Conformation Rotation Solutions Spectrum Analysis
Online-Zugang:	Volltext
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