Reduction of local tumor recurrence by excision with the CO2 laser
This study was undertaken to determine the effect of CO2 laser surgery on the incidence of local recurrence following tumor resection. Thirty female Fisher 344 rats were implanted with R3230AC mammary carcinoma. All tumors were completely excised 18–21 days post‐implantation. In 15 animals, the rese...
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| Veröffentlicht in: | Lasers in surgery and medicine 1986, Vol.6 (5), p.439-441 |
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| container_title | Lasers in surgery and medicine |
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| creator | Lanzafame, Raymond J. Rogers, David W. Nairn, John O. Defranco, Cecilia A. Ochej, Helen Raymond Hinshaw, J. |
| description | This study was undertaken to determine the effect of CO2 laser surgery on the incidence of local recurrence following tumor resection. Thirty female Fisher 344 rats were implanted with R3230AC mammary carcinoma. All tumors were completely excised 18–21 days post‐implantation.
In 15 animals, the resection was done with a scalpel. Fifteen animals underwent laser excision with the Sharplan 733 CO2 laser (TEMoo, 125mm handpiece, 25W continuous wave).
Primary tumor size was 17.6 ± 1.4mm in the scalpel group and 21.2 ± 6.3mm in the laser group. Tumor recurred in 14/15 (93.4%) of the scalpel group and 5/ 15 (33.3%) of the laser group (p |
| doi_str_mv | 10.1002/lsm.1900060503 |
| format | Article |
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In 15 animals, the resection was done with a scalpel. Fifteen animals underwent laser excision with the Sharplan 733 CO2 laser (TEMoo, 125mm handpiece, 25W continuous wave).
Primary tumor size was 17.6 ± 1.4mm in the scalpel group and 21.2 ± 6.3mm in the laser group. Tumor recurred in 14/15 (93.4%) of the scalpel group and 5/ 15 (33.3%) of the laser group (p<0.001). The site of recurrence was incisional in 13/15 (86.7%) of the scalpel group and 3/15 (20%) of the laser group (p<0.001). Axillary metastases occurred in 2/15 (13.3%) in each group. The disease‐free interval was 26 days in the laser group and 12 days in the scalpel group. The CO2 laser is an effective surgical adjunct to reduce local tumor seeding and recurrence.</description><identifier>ISSN: 0196-8092</identifier><identifier>EISSN: 1096-9101</identifier><identifier>DOI: 10.1002/lsm.1900060503</identifier><identifier>PMID: 3100889</identifier><identifier>CODEN: LSMEDI</identifier><language>eng</language><publisher>New York: John Wiley & Sons, Inc</publisher><subject>Animals ; Biological and medical sciences ; Carbon Dioxide ; CO2 laser ; excision ; Female ; Laser Therapy ; Mammary Neoplasms, Experimental - surgery ; Medical sciences ; Neoplasm Recurrence, Local ; Other treatments ; Rats ; Rats, Inbred F344 ; rodent mammary carcinoma ; Treatment. General aspects ; tumor ; tumor recurrence ; Tumors</subject><ispartof>Lasers in surgery and medicine, 1986, Vol.6 (5), p.439-441</ispartof><rights>Copyright © 1986 Wiley‐Liss, Inc., A Wiley Company</rights><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Flsm.1900060503$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Flsm.1900060503$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,4010,27900,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7984933$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3100889$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lanzafame, Raymond J.</creatorcontrib><creatorcontrib>Rogers, David W.</creatorcontrib><creatorcontrib>Nairn, John O.</creatorcontrib><creatorcontrib>Defranco, Cecilia A.</creatorcontrib><creatorcontrib>Ochej, Helen</creatorcontrib><creatorcontrib>Raymond Hinshaw, J.</creatorcontrib><title>Reduction of local tumor recurrence by excision with the CO2 laser</title><title>Lasers in surgery and medicine</title><addtitle>Lasers Surg. Med</addtitle><description>This study was undertaken to determine the effect of CO2 laser surgery on the incidence of local recurrence following tumor resection. Thirty female Fisher 344 rats were implanted with R3230AC mammary carcinoma. All tumors were completely excised 18–21 days post‐implantation.
In 15 animals, the resection was done with a scalpel. Fifteen animals underwent laser excision with the Sharplan 733 CO2 laser (TEMoo, 125mm handpiece, 25W continuous wave).
Primary tumor size was 17.6 ± 1.4mm in the scalpel group and 21.2 ± 6.3mm in the laser group. Tumor recurred in 14/15 (93.4%) of the scalpel group and 5/ 15 (33.3%) of the laser group (p<0.001). The site of recurrence was incisional in 13/15 (86.7%) of the scalpel group and 3/15 (20%) of the laser group (p<0.001). Axillary metastases occurred in 2/15 (13.3%) in each group. The disease‐free interval was 26 days in the laser group and 12 days in the scalpel group. The CO2 laser is an effective surgical adjunct to reduce local tumor seeding and recurrence.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Carbon Dioxide</subject><subject>CO2 laser</subject><subject>excision</subject><subject>Female</subject><subject>Laser Therapy</subject><subject>Mammary Neoplasms, Experimental - surgery</subject><subject>Medical sciences</subject><subject>Neoplasm Recurrence, Local</subject><subject>Other treatments</subject><subject>Rats</subject><subject>Rats, Inbred F344</subject><subject>rodent mammary carcinoma</subject><subject>Treatment. General aspects</subject><subject>tumor</subject><subject>tumor recurrence</subject><subject>Tumors</subject><issn>0196-8092</issn><issn>1096-9101</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEtPwzAQhC0EKqVw5YbkA-IWsLOJH0eoeEkFRAH1aNmOowaSptiJSv89Rq3KaXc136w0g9ApJZeUkPSqDs0llYQQRnICe2hIiWSJpITuoyGhcRdEpofoKITPSEFK-AANIHqFkEN0M3VFb7uqXeC2xHVrdY27vmk99s723ruFddissfuxVfijVlU3x93c4fFLimsdnD9GB6WugzvZzhH6uLt9Hz8kk5f7x_H1JKkgBUhKY2yZCbCMZrl1QhRQ0Fwyqh0TwDXThcjAcFFSmTPKgBQxkDGMyjIzJoURutj8Xfr2u3ehU00VrKtrvXBtHxTnaZ4z4BE824K9aVyhlr5qtF-rbeion291HWLe0utFDLfDuBSZBIiY3GCrqnbrnUyJ-itexeLVf_Fq8vb0f0VvsvFWoXM_O6_2X4px4LmaPd8rNpnezfLXqRLwC7KWhDw</recordid><startdate>1986</startdate><enddate>1986</enddate><creator>Lanzafame, Raymond J.</creator><creator>Rogers, David W.</creator><creator>Nairn, John O.</creator><creator>Defranco, Cecilia A.</creator><creator>Ochej, Helen</creator><creator>Raymond Hinshaw, J.</creator><general>John Wiley & Sons, Inc</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>1986</creationdate><title>Reduction of local tumor recurrence by excision with the CO2 laser</title><author>Lanzafame, Raymond J. ; Rogers, David W. ; Nairn, John O. ; Defranco, Cecilia A. ; Ochej, Helen ; Raymond Hinshaw, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i3233-fbbcf483c6145ce88d3d15961ae6837a6ad843b78f19561630d503bb619f4bb23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Carbon Dioxide</topic><topic>CO2 laser</topic><topic>excision</topic><topic>Female</topic><topic>Laser Therapy</topic><topic>Mammary Neoplasms, Experimental - surgery</topic><topic>Medical sciences</topic><topic>Neoplasm Recurrence, Local</topic><topic>Other treatments</topic><topic>Rats</topic><topic>Rats, Inbred F344</topic><topic>rodent mammary carcinoma</topic><topic>Treatment. General aspects</topic><topic>tumor</topic><topic>tumor recurrence</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lanzafame, Raymond J.</creatorcontrib><creatorcontrib>Rogers, David W.</creatorcontrib><creatorcontrib>Nairn, John O.</creatorcontrib><creatorcontrib>Defranco, Cecilia A.</creatorcontrib><creatorcontrib>Ochej, Helen</creatorcontrib><creatorcontrib>Raymond Hinshaw, J.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Lasers in surgery and medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lanzafame, Raymond J.</au><au>Rogers, David W.</au><au>Nairn, John O.</au><au>Defranco, Cecilia A.</au><au>Ochej, Helen</au><au>Raymond Hinshaw, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reduction of local tumor recurrence by excision with the CO2 laser</atitle><jtitle>Lasers in surgery and medicine</jtitle><addtitle>Lasers Surg. Med</addtitle><date>1986</date><risdate>1986</risdate><volume>6</volume><issue>5</issue><spage>439</spage><epage>441</epage><pages>439-441</pages><issn>0196-8092</issn><eissn>1096-9101</eissn><coden>LSMEDI</coden><abstract>This study was undertaken to determine the effect of CO2 laser surgery on the incidence of local recurrence following tumor resection. Thirty female Fisher 344 rats were implanted with R3230AC mammary carcinoma. All tumors were completely excised 18–21 days post‐implantation.
In 15 animals, the resection was done with a scalpel. Fifteen animals underwent laser excision with the Sharplan 733 CO2 laser (TEMoo, 125mm handpiece, 25W continuous wave).
Primary tumor size was 17.6 ± 1.4mm in the scalpel group and 21.2 ± 6.3mm in the laser group. Tumor recurred in 14/15 (93.4%) of the scalpel group and 5/ 15 (33.3%) of the laser group (p<0.001). The site of recurrence was incisional in 13/15 (86.7%) of the scalpel group and 3/15 (20%) of the laser group (p<0.001). Axillary metastases occurred in 2/15 (13.3%) in each group. The disease‐free interval was 26 days in the laser group and 12 days in the scalpel group. The CO2 laser is an effective surgical adjunct to reduce local tumor seeding and recurrence.</abstract><cop>New York</cop><pub>John Wiley & Sons, Inc</pub><pmid>3100889</pmid><doi>10.1002/lsm.1900060503</doi><tpages>3</tpages></addata></record> |
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| identifier | ISSN: 0196-8092 |
| ispartof | Lasers in surgery and medicine, 1986, Vol.6 (5), p.439-441 |
| issn | 0196-8092 1096-9101 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Animals Biological and medical sciences Carbon Dioxide CO2 laser excision Female Laser Therapy Mammary Neoplasms, Experimental - surgery Medical sciences Neoplasm Recurrence, Local Other treatments Rats Rats, Inbred F344 rodent mammary carcinoma Treatment. General aspects tumor tumor recurrence Tumors |
| title | Reduction of local tumor recurrence by excision with the CO2 laser |
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