Coronary artery bypass grafting within 30 days of an acute myocardial infarction

Risks and benefits of performing coronary artery bypass grafting (CABG) within 30 days of an acute myocardial infarction (AMI) were examined. In 642 patients operated on between January 1988 and December 1993, emergent CABG was performed in 46 patients for cardiogenic shock mainly for failed thrombo...

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Veröffentlicht in:The Annals of thoracic surgery 1995-05, Vol.59 (5), p.1169-1176
Hauptverfasser: Kaul, Tej K., Fields, Barry L., Riggins, Shefton L., Dacumos, Guillermo C., Wyatt, David A., Jones, Christopher R.
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container_issue 5
container_start_page 1169
container_title The Annals of thoracic surgery
container_volume 59
creator Kaul, Tej K.
Fields, Barry L.
Riggins, Shefton L.
Dacumos, Guillermo C.
Wyatt, David A.
Jones, Christopher R.
description Risks and benefits of performing coronary artery bypass grafting (CABG) within 30 days of an acute myocardial infarction (AMI) were examined. In 642 patients operated on between January 1988 and December 1993, emergent CABG was performed in 46 patients for cardiogenic shock mainly for failed thrombolysis in patients with an evolving AMI. The remaining patients underwent urgent (72 hours) revascularization for failed percutaneous transluminal coronary angioplasty (n = 73), postinfarction angina (n = 381), vein graft stenosis (n = 100), and complications after an AMI (n = 42). In patients who underwent primary CABG for an uncomplicated AMI, the infarct was subendocardial in 68, anterolateral or septal in 200, inferior or posteroinferior in 200, and posterolateral in 32 patients. Early mortality (
doi_str_mv 10.1016/0003-4975(95)00125-5
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In 642 patients operated on between January 1988 and December 1993, emergent CABG was performed in 46 patients for cardiogenic shock mainly for failed thrombolysis in patients with an evolving AMI. The remaining patients underwent urgent (&lt;72 hours) or elective (&gt;72 hours) revascularization for failed percutaneous transluminal coronary angioplasty (n = 73), postinfarction angina (n = 381), vein graft stenosis (n = 100), and complications after an AMI (n = 42). In patients who underwent primary CABG for an uncomplicated AMI, the infarct was subendocardial in 68, anterolateral or septal in 200, inferior or posteroinferior in 200, and posterolateral in 32 patients. Early mortality (&lt;30 days) was 5.9% for the entire series and 0%, 4.5%, 4.5%, 29%, 9%, 8%, 10%, and 26% for the subsets of patients with subendocardial infarct, anterolateral or septal infarct, inferior or posteroinferior infarct, ischemic mitral regurgitation, left ventricular aneurysm, redo CABG, age more than 70 years, and left ventricular ejection fraction less than 0.30, respectively. By multivariate analysis, independent predictors of early mortality were left ventricular ejection fraction less than 0.30, age more than 70 years, and cardiogenic shock. Five-year survival for the subsets of patients with subendocardial infarct, anterolateral or septal infarct, inferior or postero-inferior infarct, ischemic mitral regurgitation, left ventricular aneurysm, redo CABG, age greater than 70 years, and left ventricular ejection fraction less than 0.30 were 94%, 75%, 70%, 39%, 88%, 74%, 73%, and 52%; and cardiac event-free survivals were 66%, 68%, 73%, 22%, 68%, 62%, 62%, and 42%, respectively. Emergent or urgent CABG for AMI is indicated in case of evolving AMI with failed tissue plasminogen activator or percutaneous transluminal coronary angioplasty, postinfarction angina, and complications after AMI. 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In 642 patients operated on between January 1988 and December 1993, emergent CABG was performed in 46 patients for cardiogenic shock mainly for failed thrombolysis in patients with an evolving AMI. The remaining patients underwent urgent (&lt;72 hours) or elective (&gt;72 hours) revascularization for failed percutaneous transluminal coronary angioplasty (n = 73), postinfarction angina (n = 381), vein graft stenosis (n = 100), and complications after an AMI (n = 42). In patients who underwent primary CABG for an uncomplicated AMI, the infarct was subendocardial in 68, anterolateral or septal in 200, inferior or posteroinferior in 200, and posterolateral in 32 patients. Early mortality (&lt;30 days) was 5.9% for the entire series and 0%, 4.5%, 4.5%, 29%, 9%, 8%, 10%, and 26% for the subsets of patients with subendocardial infarct, anterolateral or septal infarct, inferior or posteroinferior infarct, ischemic mitral regurgitation, left ventricular aneurysm, redo CABG, age more than 70 years, and left ventricular ejection fraction less than 0.30, respectively. By multivariate analysis, independent predictors of early mortality were left ventricular ejection fraction less than 0.30, age more than 70 years, and cardiogenic shock. Five-year survival for the subsets of patients with subendocardial infarct, anterolateral or septal infarct, inferior or postero-inferior infarct, ischemic mitral regurgitation, left ventricular aneurysm, redo CABG, age greater than 70 years, and left ventricular ejection fraction less than 0.30 were 94%, 75%, 70%, 39%, 88%, 74%, 73%, and 52%; and cardiac event-free survivals were 66%, 68%, 73%, 22%, 68%, 62%, 62%, and 42%, respectively. Emergent or urgent CABG for AMI is indicated in case of evolving AMI with failed tissue plasminogen activator or percutaneous transluminal coronary angioplasty, postinfarction angina, and complications after AMI. Early revascularization is preferred in patients with an uncomplicated AMI in the presence of persistent ischemia or life-threatening coronary anatomy.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Coronary Artery Bypass</subject><subject>Coronary heart disease</subject><subject>Female</subject><subject>Heart</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Myocardial Infarction - complications</subject><subject>Myocardial Infarction - mortality</subject><subject>Myocardial Infarction - surgery</subject><subject>Postoperative Complications</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Survival Rate</subject><subject>Time Factors</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtrGzEURkVoSJ3HP2hBixLaxSTSaDSyNoVimiYQSBfNWlxfSanKWHKlcYL_fTSx8TKri_jOfegQ8omzK854f80YE02nlfyq5TfGeCsbeURmXMq26VupP5DZAflITkv5V59tjU_IiVJCKC5n5Pci5RQhbynk0dWy3K6hFPqUwY8hPtGXMP4NkQpGLWwLTZ5CpICb0dHVNiFkG2CgIXrIOIYUz8mxh6G4i309I483P_8sbpv7h193ix_3DUrRjQ1HD1rPFbMosRedVXxpHWip-uneOYgepXcKBOusRmaltsqhx37Jwc_n4oxc7uauc_q_cWU0q1DQDQNElzbFKNVWEaytYLcDMadSsvNmncOq_thwZiaRZrJkpq1GS_Mm0sja9nk_f7NcOXto2pur-Zd9DgVh8BkihnLAhFSi7abt33eYqy6eg8umYHARnQ3Z4WhsCu_f8QpyJ476</recordid><startdate>19950501</startdate><enddate>19950501</enddate><creator>Kaul, Tej K.</creator><creator>Fields, Barry L.</creator><creator>Riggins, Shefton L.</creator><creator>Dacumos, Guillermo C.</creator><creator>Wyatt, David A.</creator><creator>Jones, Christopher R.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19950501</creationdate><title>Coronary artery bypass grafting within 30 days of an acute myocardial infarction</title><author>Kaul, Tej K. ; Fields, Barry L. ; Riggins, Shefton L. ; Dacumos, Guillermo C. ; Wyatt, David A. ; Jones, Christopher R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c534t-1cfa99870dc5c634d71bdea957649758a36c5fe7a304d9c0d59d7ecfc6b1af883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Coronary Artery Bypass</topic><topic>Coronary heart disease</topic><topic>Female</topic><topic>Heart</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Myocardial Infarction - complications</topic><topic>Myocardial Infarction - mortality</topic><topic>Myocardial Infarction - surgery</topic><topic>Postoperative Complications</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Survival Rate</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kaul, Tej K.</creatorcontrib><creatorcontrib>Fields, Barry L.</creatorcontrib><creatorcontrib>Riggins, Shefton L.</creatorcontrib><creatorcontrib>Dacumos, Guillermo C.</creatorcontrib><creatorcontrib>Wyatt, David A.</creatorcontrib><creatorcontrib>Jones, Christopher R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kaul, Tej K.</au><au>Fields, Barry L.</au><au>Riggins, Shefton L.</au><au>Dacumos, Guillermo C.</au><au>Wyatt, David A.</au><au>Jones, Christopher R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coronary artery bypass grafting within 30 days of an acute myocardial infarction</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>1995-05-01</date><risdate>1995</risdate><volume>59</volume><issue>5</issue><spage>1169</spage><epage>1176</epage><pages>1169-1176</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Risks and benefits of performing coronary artery bypass grafting (CABG) within 30 days of an acute myocardial infarction (AMI) were examined. In 642 patients operated on between January 1988 and December 1993, emergent CABG was performed in 46 patients for cardiogenic shock mainly for failed thrombolysis in patients with an evolving AMI. The remaining patients underwent urgent (&lt;72 hours) or elective (&gt;72 hours) revascularization for failed percutaneous transluminal coronary angioplasty (n = 73), postinfarction angina (n = 381), vein graft stenosis (n = 100), and complications after an AMI (n = 42). In patients who underwent primary CABG for an uncomplicated AMI, the infarct was subendocardial in 68, anterolateral or septal in 200, inferior or posteroinferior in 200, and posterolateral in 32 patients. Early mortality (&lt;30 days) was 5.9% for the entire series and 0%, 4.5%, 4.5%, 29%, 9%, 8%, 10%, and 26% for the subsets of patients with subendocardial infarct, anterolateral or septal infarct, inferior or posteroinferior infarct, ischemic mitral regurgitation, left ventricular aneurysm, redo CABG, age more than 70 years, and left ventricular ejection fraction less than 0.30, respectively. By multivariate analysis, independent predictors of early mortality were left ventricular ejection fraction less than 0.30, age more than 70 years, and cardiogenic shock. Five-year survival for the subsets of patients with subendocardial infarct, anterolateral or septal infarct, inferior or postero-inferior infarct, ischemic mitral regurgitation, left ventricular aneurysm, redo CABG, age greater than 70 years, and left ventricular ejection fraction less than 0.30 were 94%, 75%, 70%, 39%, 88%, 74%, 73%, and 52%; and cardiac event-free survivals were 66%, 68%, 73%, 22%, 68%, 62%, 62%, and 42%, respectively. Emergent or urgent CABG for AMI is indicated in case of evolving AMI with failed tissue plasminogen activator or percutaneous transluminal coronary angioplasty, postinfarction angina, and complications after AMI. Early revascularization is preferred in patients with an uncomplicated AMI in the presence of persistent ischemia or life-threatening coronary anatomy.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>7733715</pmid><doi>10.1016/0003-4975(95)00125-5</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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subjects Aged
Biological and medical sciences
Cardiology. Vascular system
Coronary Artery Bypass
Coronary heart disease
Female
Heart
Hospital Mortality
Humans
Male
Medical sciences
Myocardial Infarction - complications
Myocardial Infarction - mortality
Myocardial Infarction - surgery
Postoperative Complications
Retrospective Studies
Risk Factors
Survival Rate
Time Factors
title Coronary artery bypass grafting within 30 days of an acute myocardial infarction
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