The role of calcium in the regulation of free radical reduction by thioredoxin reductase at the surface of the skin

Membrane associated thioredoxin reductase has been previously shown to reduce free radicals on the outer plasma membranes of human keratinocytes and melanocytes to provide a possible first line of defense against free radical damage at the surface of the skin [1]. Preliminary experiments with cell c...

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Veröffentlicht in:	Journal of inorganic biochemistry 1986-10, Vol.28 (2), p.227-238
Hauptverfasser:	Schallreuter, K.U., Pittelkow, M.R., Gleason, F.K., Wood, J.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analytical, structural and metabolic biochemistry Animals Applied sciences Biological and medical sciences Calcium - pharmacology Cells, Cultured Electron Spin Resonance Spectroscopy Enzymes and enzyme inhibitors Exact sciences and technology Fundamental and applied biological sciences. Psychology Guinea Pigs Humans Infant, Newborn Keratins - metabolism Kinetics Melanocytes - metabolism NADH, NADPH Oxidoreductases - metabolism Other techniques and industries Oxidoreductases Skin - enzymology Thioredoxin-Disulfide Reductase - metabolism
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