Progression of subcellular changes during chemical hypoxia to cultured rat hepatocytes: A laser scanning confocal microscopic study

The aim of this study was to evaluate changes in the subcellular organelles of cultured hepatocytes by laser scanning confocal microscopy during chemical hypoxia with cyanide and iodoacetate, inhibitors of mitochon‐drial respiration and glycolysis, respectively. Parameter‐specific fluorophores used...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 1995-05, Vol.21 (5), p.1361-1372
Hauptverfasser:	Zahrebelski, George, Nieminen, Anna‐Liisa, Al‐Ghoul, Kristin, Qian, Ting, Herman, Brian, Lemasters, John J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal cells Animals Biological and medical sciences Cell cultures. Hybridization. Fusion Cell Death Cells, Cultured Electrophysiology Extracellular Space - metabolism Fluoresceins - pharmacokinetics Fundamental and applied biological sciences. Psychology Hypoxia - chemically induced Hypoxia - pathology Image Processing, Computer-Assisted Indicators and Reagents Lysosomes - ultrastructure Male Microscopy, Confocal Mitochondria, Liver - metabolism Mitochondria, Liver - physiology Molecular and cellular biology Propidium - pharmacokinetics Rats Rats, Sprague-Dawley
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